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8.52096

Fmoc-Lys(Dabcyl)-OH

≥97% (TLC), for peptide synthesis, Novabiochem®

Synonym(s):

Fmoc-Lys(Dabcyl)-OH

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About This Item

Empirical Formula (Hill Notation):
C36H37N5O5
CAS Number:
146998-27-8
Molecular Weight:
619.71
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
MFCD00467694
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Product Name

Fmoc-Lys(Dabcyl)-OH, Novabiochem®

Quality Level

200

product line

Novabiochem®

assay

≥95.5% (HPLC), ≥97% (TLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

N([C@@H](CCCCNC(=O)c4ccc(cc4)N=Nc5ccc(cc5)N(C)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C36H37N5O5/c1-41(2)27-20-18-26(19-21-27)40-39-25-16-14-24(15-17-25)34(42)37-22-8-7-13-33(35(43)44)38-36(45)46-23-32-30-11-5-3-9-28(30)29-10-4-6-12-31(29)32/h3-6,9-12,14-21,32-33H,7-8,13,22-23H2,1-2H3,(H,37,42)(H,38,45)(H,43,44)/t33-/m0/s1

InChI key

FPOPWTDBGMLRNG-XIFFEERXSA-N

General description

A modified lysine derivative for the preparation of chromogenically-labeled peptides by Fmoc SPPS. The Dabcyl group quenches the fluorescence of EDANS, Mca, TET, JOE, FAM fluorophores, making it an extremely useful tool for the synthesis of fluorescence-quenched peptide substrates.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Chromogenic Labeling of Synthetic Peptides

Analysis Note

Color (visual): orange to red
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(157B)): ≥ 97 %
Assay (HPLC, area%): ≥ 95.5 % (a/a)

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1236

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品

This item has

Certificates of Analysis (COA)

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Articles

Peptide Labeling

Chromogenic and fluorogenic derivatives are invaluable tools for biochemistry, having numerous applications in enzymology, protein chemistry, immunology and histochemistry.

Global Trade Item Number

SKUGTIN
852096000104027269089221
852096850004027269089238