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About This Item
Empirical Formula (Hill Notation):
C9H7N7O2S
CAS Number:
Molecular Weight:
277.26
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
pharmaceutical primary standard
API family
azathioprine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
Cn1cnc(c1Sc2ncnc3[nH]cnc23)[N+]([O-])=O
InChI
1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)
InChI key
LMEKQMALGUDUQG-UHFFFAOYSA-N
Gene Information
human ... PPAT(5471)
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Azathioprine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
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Manuel Rodríguez-Perálvarez et al.
Current opinion in organ transplantation, 19(3), 253-260 (2014-04-02)
Long-term survival of liver transplant recipients is threatened by increased rates of de-novo malignancy and recurrence of hepatocellular carcinoma (HCC), both events tightly related to immunosuppression. There is accumulating evidence linking increased exposure to immunosuppressants and carcinogenesis, particularly concerning calcineurin
Helen French et al.
Digestive diseases and sciences, 56(7), 1929-1936 (2011-04-09)
The duration of use of azathioprine (Aza) and 6-mercaptopurine (6-MP) for maintaining remission for Crohn's disease is debatable. To examine whether Aza/6-MP can be safely withdrawn in patients with Crohn's disease who have been in remission. The following databases were
D Dooremont et al.
Acta gastro-enterologica Belgica, 76(3), 342-346 (2013-11-23)
We report 3 male IBD patients (2 Crohn's Disease, 1 Ulcerative Colitis) developing thrombocytopenia and splenomegaly on azathioprine treatment. All patients were diagnosed with significant portal hypertension due to histological proven nodular regenerative hyperplasia (NRH) of the liver. In two
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A1500000 | 04061833342374 |