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BP100

Dacarbazine

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide, DTIC

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About This Item

Empirical Formula (Hill Notation):
C6H10N6O
CAS Number:
4342-03-4
Molecular Weight:
182.18
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
224-396-1
MDL number:
MFCD00057167
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grade

pharmaceutical primary standard

API family

dacarbazine

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

CN(C)\N=N\c1[nH]cnc1C(N)=O

InChI

1S/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)/b11-10+

InChI key

FDKXTQMXEQVLRF-ZHACJKMWSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dacarbazine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Dacarbazine Injection

    • Packaging

    Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

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    signalword

    Danger

    Storage Class

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    pictograms

    Health hazard
    GHS08

    hcodes

    H340,H350

    Hazard Classifications

    Carc. 1B - Muta. 1B

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    Certificates of Analysis (COA)

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    Junwei Hou et al.
    Nature cell biology, 22(10), 1264-1275 (2020-09-16)
    Although pyroptosis is critical for macrophages against pathogen infection, its role and mechanism in cancer cells remains unclear. PD-L1 has been detected in the nucleus, with unknown function. Here we show that PD-L1 switches TNFα-induced apoptosis to pyroptosis in cancer

    Global Trade Item Number

    SKUGTIN
    BP10004061835277896