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D1954000

Dihydrostreptomycin sulfate

Name: Dihydrostreptomycin sulfate
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dihydrostreptomycin sesquisulfate

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About This Item

Linear Formula:

C₂₁H₄₁N₇O₁₂ · 3/2H₂SO₄

CAS Number:

5490-27-7

Molecular Weight:

730.71

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329798719

EC Number:

226-823-7

Beilstein/REAXYS Number:

3894221

MDL number:

MFCD00070252

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Properties

grade

pharmaceutical primary standard

API family

dihydrostreptomycin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@@H](O[C@@H](C)[C@]2(O)CO)O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]3NC(N)=N.CN[C@H]4[C@H](O)[C@@H](O)[C@H](CO)O[C@H]4O[C@H]5[C@@H](O[C@@H](C)[C@]5(O)CO)O[C@@H]6[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]6NC(N)=N

InChI

1S/2C21H41N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*5-18,26,29-36H,3-4H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,21+;;;/m00.../s1

InChI key

CZWJCQXZZJHHRH-YZTFXSNBSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dihydrostreptomycin sulfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302,H361fd

pcodes

P201 - P301 + P312 + P330 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品

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A high-throughput analytical method for determination of aminoglycosides in veal tissues by liquid chromatography/tandem mass spectrometry with automated cleanup.

Yves Babin et al.

Journal of AOAC International, 90(5), 1418-1426 (2007-10-25)

A liquid chromatographic/tandem mass spectrometric (LC/MS/MS) method was developed for determining dihydrostreptomycin, gentamicin C1, and neomycin in veal kidney, liver, and muscle. The extraction prior to injection on the automated cleanup/analysis system is very simple, permitting preparation of 24 veal

Hydrophilic interaction vs ion pair liquid chromatography for the determination of streptomycin and dihydrostreptomycin residues in milk based on mass spectrometric detection.

Aikaterini M Gremilogianni et al.

Journal of chromatography. A, 1217(43), 6646-6651 (2010-06-16)

Streptomycin (STR) and dihydrostreptomycin (DHSTR) are two of the most common aminoglycoside antibiotics used in veterinary medicine. The physicochemical properties of both substances, make their determination challenging. In the present study the development of methods based on ion-pair chromatography (IPC)

Comparison of Campylobacter isolated from humans and food-producing animals in Japan.

K Ishihara et al.

Journal of applied microbiology, 100(1), 153-160 (2006-01-13)

To compare the antimicrobial resistance, serotypes and flagellin gene types of Campylobacter isolated from humans and food-producing animals and thereby facilitate elucidation of the origin of Campylobacter causing human infection in Japan. The MIC values of ampicillin, dihydrostreptomycin, gentamicin, erythromycin

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Global Trade Item Number

SKU	GTIN
D1954000	04061833792933