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E1900000

Ethinylestradiol

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

17α-Ethynylestradiol, 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol, 19-Nor-1,3,5(10),17α-pregnatrien-20-yne-3,17-diol, Ethinylestradiol

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About This Item

Empirical Formula (Hill Notation):
C20H24O2
CAS Number:
57-63-6
Molecular Weight:
296.40
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329799022
MDL number:
MFCD00003690
Beilstein/REAXYS Number:
2419975
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grade

pharmaceutical primary standard

API family

ethinyl estradiol

manufacturer/tradename

EDQM

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

182-183 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]3(O)C#C)[C@]1([H])CCc4cc(O)ccc24

InChI

1S/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17-,18+,19+,20+/m1/s1

InChI key

BFPYWIDHMRZLRN-SLHNCBLASA-N

Gene Information

human ... ESR1(2099)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ethinylestradiol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 1 - Carc. 2 - Repr. 1A

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Regulatory Information

涉药品监管产品

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C Piérard-Franchimont et al.
Maturitas, 22(2), 151-154 (1995-09-01)
The effects of menopause and hormone replacement therapy (HRT) on the epidermis are largely unknown. The aim of this study was to model and measure the influence of estrogen-transdermal HRT on subtle physiological changes taking place in the epidermis during
Jie Han et al.
Water research, 47(7), 2273-2284 (2013-03-08)
This study demonstrates that ethinylestradiol (EE2), a priority estrogenic contaminant in water, can be rapidly and selectively removed from aqueous solutions using industrial-grade polyamide 612 (PA612) particles as adsorbents. Isothermal studies showed that nonporous low surface area (20 m(2) g(-1)) PA612 particles
Bernardine H Stegeman et al.
BMJ (Clinical research ed.), 347, f5298-f5298 (2013-09-14)
To provide a comprehensive overview of the risk of venous thrombosis in women using different combined oral contraceptives. Systematic review and network meta-analysis. PubMed, Embase, Web of Science, Cochrane, Cumulative Index to Nursing and Allied Health Literature, Academic Search Premier
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Global Trade Item Number

SKUGTIN
E190000004061833602300