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About This Item
Empirical Formula (Hill Notation):
C23H27N5O7S · H2O
CAS Number:
Molecular Weight:
535.57
UNSPSC Code:
41116107
NACRES:
NA.24
grade
pharmaceutical primary standard
API family
piperacillin
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
SMILES string
S1[C@H]2N([C@H](C1(C)C)C(=O)O)C(=O)[C@H]2NC(=O)[C@H](NC(=O)N4CCN(C(=O)C4=O)CC)c3ccccc3.O
InChI
1S/C23H27N5O7S.H2O/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28;/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34);1H2/t13-,14-,15+,20-;/m1./s1
InChI key
NBXPLBPWMYNZTC-IDYPWDAWSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Piperacillin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Skin Sens. 1B
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
涉药品监管产品
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Sangil Jeon et al.
Antimicrobial agents and chemotherapy, 58(7), 3744-3751 (2014-04-23)
Piperacillin in combination with tazobactam, a β-lactamase inhibitor, is a commonly used intravenous antibiotic for the empirical treatment of infection in intensive care patients, including burn patients. The purpose of this study was to develop a population pharmacokinetic (PK) model
Ashley W Sturm et al.
Pharmacotherapy, 34(1), 28-35 (2013-07-19)
To evaluate the steady-state pharmacokinetic and pharmacodynamic parameters of piperacillin in morbidly obese, surgical intensive care patients. Open-label single-center prospective study. Level I trauma center and university-affiliated teaching institution. Nine morbidly obese (body mass index [BMI] 40.0 kg/m² or higher)
Brian D VanScoy et al.
Antimicrobial agents and chemotherapy, 58(10), 6024-6031 (2014-07-30)
It is important to understand the relationship between antibiotic exposure and the selection of drug resistance in the context of therapy exposure. We sought to identify the ceftolozane-tazobactam exposure necessary to prevent the amplification of drug-resistant bacterial subpopulations in a
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P1890000 | 04061834357117 |