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PHR1000

Dextrose

Name: Dextrose
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

D-(+)-Glucose, Dextrose

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₂O₆

CAS Number:

50-99-7

Molecular Weight:

180.16

NACRES:

NA.24

PubChem Substance ID:

329823031

UNSPSC Code:

12352201

EC Number:

200-075-1

Beilstein/REAXYS Number:

1724615

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Properties

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0001745, traceable to USP 1181302

API family

dextrose

assay

99.9%

CofA

current certificate can be downloaded

analyte chemical class(es)

oligosaccharides

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

150-152 °C (lit.)

application(s)

detection
food and beverages
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Description

General description

Dextrose belongs to the class of sugars, and is a preferred source of carbohydrate in parenteral nutrition regimens. It is widely used in solutions to adjust tonicity, as a sweetening agent, wet granulation diluent/binder, direct-compression tablet diluent/binder, etc. It is considered only for short term clinical use, since it is deficient in electrolytes.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Dextrose has been used as a standard in the determination of additives like glucose in beverages using high performance liquid chromatography (HPLC). It may also be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB7785 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c