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PHR1046

Ethylene glycol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Monoethylene glycol, 1,2-Ethanediol

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About This Item

Linear Formula:
HOCH2CH2OH
CAS Number:
107-21-1
Molecular Weight:
62.07
NACRES:
NA.24
PubChem Substance ID:
329823076
eCl@ss:
39020501
UNSPSC Code:
41116107
EC Number:
203-473-3
MDL number:
MFCD00002885
Beilstein/REAXYS Number:
505945
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Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1265515

vapor density

2.1 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

752 °F

expl. lim.

15.3 %

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.431 (lit.)

bp

195-198 °C

mp

−13 °C (lit.)

density

1.113 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ethylene glycol can also be produced from fossil fuels (petroleum, natural gas and coal) and biomass-derived resources. It is a polyol having a wide range of industrial applications.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Ethylene glycol may be used as a standard in the determination of ethylene glycol present in serum samples using gas chromatography (GC).

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC2089 in the slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

hcodes

H302,H373

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2 Oral

target_organs

Kidney

Storage Class

10 - Combustible liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Protocols

利用 Nukol™ 对乙二醇类进行气相色谱分析

99%；甘油，≥99.5%；四甘醇，99%

Articles

GC-MS Analysis of Lithium Ion Battery Electrolyte Solvents

Analysis of carbonate solvents in lithium-ion batteries like ethylene carbonate, dimethyl carbonate, diethyl carbonate, and more using SPB®-624 column.

Gas-chromatographic determination of ethylene glycol in serum
Porter H.W and Auansakul aA
Clinical Chemistry, 28, 75-78 (1982)
Yi Wang et al.
Journal of the American Chemical Society, 135(5), 1941-1951 (2013-01-16)
This article describes a robust method for the facile synthesis of small Ag nanocubes with edge lengths controlled in the range of 18-32 nm. The success of this new method relies on the substitution of ethylene glycol (EG)--the solvent most
Andrea Marchionni et al.
ChemSusChem, 6(3), 518-528 (2013-02-14)
The electrooxidation of ethylene glycol (EG) and glycerol (G) has been studied: in alkaline media, in passive as well as active direct ethylene glycol fuel cells (DEGFCs), and in direct glycerol fuel cells (DGFCs) containing Pd-(Ni-Zn)/C as an anode electrocatalyst
View All Related Papers

Global Trade Item Number

SKUGTIN
PHR1046-1G04061837883897