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PHR1093

Sulfanilamide melting point standard

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Sulfanilamide, p-Aminobenzenesulfonamide

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About This Item

Linear Formula:
H2NC6H4SO2NH2
CAS Number:
Molecular Weight:
172.20
NACRES:
NA.24
PubChem Substance ID:
eCl@ss:
39093202
UNSPSC Code:
41116107
EC Number:
200-563-4
MDL number:
Beilstein/REAXYS Number:
511852
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1633007

API family

sulfanilamide

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

~Approximately 166 °C, 164-166 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Nc1ccc(cc1)S(N)(=O)=O

InChI

1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

InChI key

FDDDEECHVMSUSB-UHFFFAOYSA-N

General description

Sulfanilamide Melting Point Standard also called Sulfanilamide is an antibacterial drug.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Sulfanilamide Melting Point Standard, also called Sulfanilamide, is an antibacterial drug. It blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.

Application

It was used in a study to demonstrate photodecomposition in aqueous solution of cutaneous photosensitizing agents with the help of spin traps 5, 5-dimethyl-1-pyrroline-1-oxide.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB1410 in the slot below. This is an example certificate only and may not be the lot that you receive.


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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SPECTROSCOPIC STUDIES OF CUTANEOUS PHOTOSENSITIZING AGENTS?II. SPIN TRAPPING OF PHOTOLYSIS PRODUCTS FROM SULFANILAMIDE AND 4-AMINOBENZOIC ACID USING 5, 5-DIMETHYL-1-PYRROLINE-1-OXIDE.
Chignell, Colin F., et al.
Photochemistry and Photobiology, 34.2 , 147-156 (1981)
Xian-Long Wang et al.
European journal of medicinal chemistry, 45(10), 4631-4639 (2010-08-17)
A series of novel sulfanilamide-derived 1,2,3-triazole compounds were synthesized in excellent yields via 1,3-dipolar cycloaddition and confirmed by MS, IR and NMR spectra as well as elemental analyses. All the compounds were screened in vitro for their antibacterial and antifungal
Electrophilic trifluoromethanesulfanylation of organometallic species with trifluoromethanesulfanamides.
François Baert et al.
Angewandte Chemie (International ed. in English), 51(41), 10382-10385 (2012-09-15)



Global Trade Item Number

SKUGTIN
PHR1093-1G04061835232987