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PHR2411

Guanosine

Name: Guanosine
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Guanosine, 9-(β-D-Ribofuranosyl)guanine, Guanine-9-β-D-ribofuranoside

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₃N₅O₅

CAS Number:

118-00-3

Molecular Weight:

283.24

UNSPSC Code:

41116107

NACRES:

NA.24

Beilstein/REAXYS Number:

625911

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Properties

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

description

API family: adenosine

API family

adenosine

form

solid

CofA

current certificate can be downloaded

packaging

pkg of 100 mg

mp

250 °C (dec.) (lit.)

application(s)

pharmaceutical small molecule

storage temp.

-10 to -25°C

SMILES string

[H]O[H].NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1

InChI key

NYHBQMYGNKIUIF-UUOKFMHZSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Guanosine has been used:

As an internal standard for quantification of guanosine in human cells.
As an internal standard in a single-marker quantitative assay to determine the content of nucleosides in Rhizoma Paridis.
For the determination of the analyte in vegetables using spectrometric methods.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC4523 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c