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RDD029

Guanidine thiocyanate

for molecular biology, free-flowing, Redi-Dri™, ≥99.0%

Synonym(s):

GTC, Guanidine isothiocyanate, Guanidinium rhodanide, Guanidinium thiocyanate

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About This Item

Linear Formula:
NH2C(=NH)NH2 · HSCN
CAS Number:
593-84-0
Molecular Weight:
118.16
NACRES:
NA.28
UNSPSC Code:
12352107
Beilstein/REAXYS Number:
3563461
MDL number:
MFCD00013027
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product line

Redi-Dri™

Quality Level

100

assay

≥99.0%

quality

for molecular biology, free-flowing

mp

120-122 °C (lit.)

foreign activity

DNAse, none detected, RNAse, none detected

General description

Guanadine thiocyanate (GTC) is a chaotropic agent and strong denaturant that is used in research for protein degredation in vitro. This is useful for DNA or RNA isolation and purification. GTC is a key reagent for inactivation of endogenous DNases and RNase for molecular biology techniques used to isolate nucliec acids from tissues, cells, or viral genomes.

Application

Chaotropic agent and strong denaturant; solubilizes cells.
Guanidine thiocyanate is commonly used for research:

  • to denature proteins in cell lysis buffer
  • to isolate and purify RNA from cells and tissues
  • to extract DNA from cellular and viral genomes

Biochem/physiol Actions

Guanadine thiocyanate is strong protein denaturant commonly combinded with phenol to lyse tissues, cells, and proteins during RNA isolation assay.

Features and Benefits

  • Redi-Dri™ makes working with hygroscopic chemicals easier
  • Controls moisture and powder remains free-flowing
  • Safer to handle and weigh out for routine use in lab
  • Eliminates clumps and maintains product moisture and quality attributes

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

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pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C

supp_hazards

EUH032

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
WXBD1410V
WXBD0454V

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Articles

Redi-Dri™ – The World of Free-flowing Hygroscopic Products

Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.

Global Trade Item Number

SKUGTIN
RDD029-100G04022536340784
RDD029-500G04061841124177
RDD029-1KG04061841124153
RDD029-2.5KG04061841124160