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S2159100

Sulfapyridine

Name: Sulfapyridine
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

4-Amino-N-[2-pyridyl]benzene sulfonamide, N¹-(Pyridin-2-yl)sulfanilamide

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₁N₃O₂S

CAS Number:

144-83-2

Molecular Weight:

249.29

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329824511

MDL number:

MFCD00038036

Beilstein/REAXYS Number:

222065

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Properties

grade

pharmaceutical primary standard

API family

sulfapyridine

manufacturer/tradename

EDQM

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2

InChI

1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)

InChI key

GECHUMIMRBOMGK-UHFFFAOYSA-N

Description

General description

Sulfapyridine is a metabolite of Sulfasalazine. It is an antibiotic and is mostly used in treating rheumatoid arthritis.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sulfapyridine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

GHS08

signalword

Warning

hcodes

H361fd

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

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Dapsone and sulfapyridine.

U Paniker et al.

Dermatologic clinics, 19(1), 79-86 (2001-01-13)

Dapsone and sulfapyridine are structurally related compounds with anti-microbial and anti-inflammatory effects. Dapsone remains the most important drug for leprosy and is useful in the prophylaxis of Pneumocystis pneumonia in patients with HIV disease. The medical treatment of choice for

Treatment with sulfasalazine or sulfapyridine, but not 5-aminosalicylic acid, inhibits basic fibroblast growth factor-induced endothelial cell chemotaxis.

Volin, Michael V., et al.

Arthritis and Rheumatism, 42.9, 1927-1935 (1999)