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Y0001238

Sulfinpyrazone for system suitability

Name: Sulfinpyrazone for system suitability
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(±)-Sulfinpyrazone, 1,2-Diphenyl-4-(phenylsulfinylethyl)-3,5-pyrazolidinedione, Diphenylpyrazone

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About This Item

Empirical Formula (Hill Notation):

C₂₃H₂₀N₂O₃S

CAS Number:

57-96-5

Molecular Weight:

404.48

NACRES:

NA.24

PubChem Substance ID:

329831317

UNSPSC Code:

41116107

MDL number:

MFCD00057279

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Properties

grade

pharmaceutical primary standard

API family

sulfinpyrazone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O=C1C(CCS(=O)c2ccccc2)C(=O)N(N1c3ccccc3)c4ccccc4

InChI

1S/C23H20N2O3S/c26-22-21(16-17-29(28)20-14-8-3-9-15-20)23(27)25(19-12-6-2-7-13-19)24(22)18-10-4-1-5-11-18/h1-15,21H,16-17H2

InChI key

MBGGBVCUIVRRBF-UHFFFAOYSA-N

Gene Information

human ... SLC22A12(116085)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sulfinpyrazone for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Sulfinpyrazone: relationship between dose, kinetics, plasma concentrations and biological effects.

M R Buchanan

Thrombosis research. Supplement, 4, 89-92 (1983-01-01)

Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin.

Ashley M Laughney et al.

Science translational medicine, 6(261), 261ra152-261ra152 (2014-11-08)

Eribulin mesylate was developed as a potent microtubule-targeting cytotoxic agent to treat taxane-resistant cancers, but recent clinical trials have shown that it eventually fails in many patient subpopulations for unclear reasons. To investigate its resistance mechanisms, we developed a fluorescent

Uricosuric drugs, with special reference to probenecid and sulfinpyrazone.

A B Gutman

Advances in pharmacology, 4, 91-142 (1966-01-01)

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Global Trade Item Number

SKU	GTIN
Y0001238	04061833806692