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Merck
CN

Y0001442

N-[(cis-4-Isopropylcyclohexyl)carbonyl]-D-phenylalanine

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

N-[[cis-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine

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About This Item

Empirical Formula (Hill Notation):
C19H27NO3
CAS Number:
Molecular Weight:
317.42
NACRES:
NA.24
UNSPSC Code:
41116107
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grade

pharmaceutical primary standard

API family

nateglinide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

N-[(cis-4-Isopropylcyclohexyl)carbonyl]-ᴅ-phenylalanine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Jian Zhou et al.
Diabetes technology & therapeutics, 15(6), 481-488 (2013-05-02)
Recent studies have identified postprandial glycemic excursions as risk factors for diabetes complications. This study aimed to compare the effects of nateglinide and acarbose treatments on postprandial glycemic excursions in Chinese subjects with type 2 diabetes. This was a multicenter
E Phielix et al.
Diabetes, obesity & metabolism, 15(10), 915-922 (2013-04-12)
Thiazoledinediones decrease blood glucose by their insulin-sensitizing properties. Here, we examined whether pioglitazone plus nateglinide (PIO) interferes with hepatocellular lipid (HCL) content and/or improves insulin sensitivity in well-controlled non-obese patients with type 2 diabetes mellitus (T2DM). Sixteen patients [body mass
Lauretta Maggi et al.
International journal of pharmaceutics, 454(1), 562-567 (2013-07-23)
Nateglinide is a non-sulphonylurea insulinotropic oral antidiabetic agent. The main problem in formulating an oral dosage form is its low solubility in aqueous media. This problem is particularly critical for an anti-diabetic drug because it should be administered just before



Global Trade Item Number

SKUGTIN
Y000144204061833807842