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Merck
CN

S4641

Sodium citrate tribasic dihydrate

ACS reagent grade, ≥99.0%

Synonym(s):

Citric acid trisodium salt dihydrate, Trisodium citrate dihydrate

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About This Item

Linear Formula:
HOC(COONa)(CH2COONa)2 · 2H2O
CAS Number:
Molecular Weight:
294.10
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-675-3
MDL number:
Beilstein/REAXYS Number:
6104939
Assay:
≥99.0%
Grade:
ACS reagent
Solubility:
water: soluble 29.4 g/L at 20 °C (completely)
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Product Name

Sodium citrate tribasic dihydrate, ACS reagent, ≥99.0%

grade

ACS reagent

agency

suitable for SM 4500 - NH3

assay

≥99.0%

impurities

≤0.003% Ammonia (NH3), ≤0.005% Insoluble matter

pH

7.0-9.0 (25 °C, 5% in solution)

mp

>300 °C (lit.)

solubility

water: soluble 29.4 g/L at 20 °C (completely)

anion traces

chloride (Cl-): ≤0.003%, sulfate (SO42-): ≤0.005%

cation traces

Ca: ≤0.005%, Fe: ≤5 ppm, heavy metals: ≤5 ppm (by ICP-OES)

SMILES string

O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3

InChI key

NLJMYIDDQXHKNR-UHFFFAOYSA-K

Application

Sodium citrate tribasic dihydrate can be used as a catalyst to synthesize:     
  • Fused O- and N-heterocyclic derivatives via multicomponent Knoevenagel-cyclocondensation of isatin/aldehyde/ acenaphthylene-1,2-dione, malononitrile, and various C−H activated acids.     
  • Chromeno[3′,4′:5,6]pyrano[2,3-d]pyrimidines by the condensation reaction of 4-hydroxycoumarin, aromatic aldehydes, and barbituric acid/thiobarbituric acid.

It can also be used as:      
A reducing agent to synthesize metal nanoparticles via sol-gel method using corresponding metal salt precursors.    
A controlling agent in the synthesis of single-crystal of coordination polymer [Co(H2O)2Ni(CN)4 4H2O].


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

Citrate is one of many cell culture components that affects the performance of serum-free, protein-free and animal protein-free cell culture systems used for biomanufacturing heterologous proteins such as monoclonal antibodies.

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Global Trade Item Number

SKUGTIN
S4641-500G04061835559756
S4641-1KG04061836927929
S4641-25G04061836927950
S4641-5KG04061836927981