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Merck
CN

93014

Manganese peroxidase from white-rot fungus (Phanerochaete chrysosporium)

greener alternative

powder, light brown, ≥10 U/g

Synonym(s):

Manganese-dependent lignin peroxidase, MnP, Peroxidase, manganese

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About This Item

CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
MDL number:
Specific activity:
≥10 U/g
Biological source:
fungus (white-rot fungus (Phanerochaete chrysosporium))
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biological source

fungus (white-rot fungus (Phanerochaete chrysosporium))

form

powder

specific activity

≥10 U/g

greener alternative product characteristics

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

color

light brown

greener alternative category

shipped in

wet ice

storage temp.

−20°C

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for energy efficiency and waste prevention when used in fuel cell and cellulosic ethanol research. For more information see the article in biofiles and Enzymes for Alternative Energy Research

Application

Manganese peroxidase from white-rot fungus (Phanerochaete chrysosporium) is from the peroxidase family and is used to oxidize manganese. It may be used to study wound healing.

Biochem/physiol Actions

Manganese peroxidase catalyzes the oxidation of Mn2+ to Mn3+. Mn3+ is then in complex with oxalate, which is able to oxidize lignin. Manganese peroxidase from Phanerochaete chrysosporium binds 2 calcium ions per subunit. It binds 1 heme B (iron-protoporphyrin IX) group per subunit .

Physical form

Supplied as a lyophilized powder containing ~50% sodium tartrate
only partially soluble in water or buffer

Other Notes

One unit corresponds to the amount of enzyme, which oxidizes 1 μmole Mn2+ per minute to Mn3+ at pH 4.5 and 25 °C
This product is supplied as a mixture of isozymes, mol. mass (40-65 kDa).


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

常规特殊物品

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Almasul Alfi et al.
Journal of bioscience and bioengineering, 128(3), 290-295 (2019-04-08)
Manganese peroxidase (MnP) is a fungal heme-containing enzyme which oxidizes Mn2+ to Mn3+, a diffusible and strong non-specific oxidant capable of attacking bulky phenolic substrates. Therefore, MnP is indispensable in the polymer and paper industries. Previous attempts of MnP expression
Tomer M Salame et al.
Applied and environmental microbiology, 78(15), 5341-5352 (2012-05-29)
Pleurotus ostreatus (the oyster mushroom) and other white rot filamentous basidiomycetes are key players in the global carbon cycle. P. ostreatus is also a commercially important edible fungus with medicinal properties and is important for biotechnological and environmental applications. Efficient
Pratibha Yadav et al.
Indian journal of biochemistry & biophysics, 49(1), 42-48 (2012-03-23)
Mn-peroxidase (MnP), a biotechnologically important enzyme was purified for the first time from a plant source Musa paradisiaca (banana) stem, which is an agro-waste easily available after harvest of banana fruits. MnP was earlier purified only from the fungal sources.



Global Trade Item Number

SKUGTIN
93014-100MG-F04061832727714
93014-10MG-F04061833271353