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Merck
CN

A0156

N-(4-Aminobutyl)-N-ethylisoluminol

≥90%, powder

Synonym(s):

4-(N1-Ethyl-4-aminobutylamino)phthalic hydrazide, 6-[N-(4-Aminobutyl)-N-ethylamino]-2,3-dihydro-1,4-phthalazinedione, ABEI

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About This Item

Empirical Formula (Hill Notation):
C14H20N4O2
CAS Number:
Molecular Weight:
276.33
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
Beilstein/REAXYS Number:
920895
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Product Name

N-(4-Aminobutyl)-N-ethylisoluminol, ≥90%

Quality Level

assay

≥90%

form

powder

mp

259-260 °C (lit.)

solubility

glacial acetic acid: 50 mg/mL, clear, colorless to yellow

storage temp.

2-8°C

SMILES string

CCN(CCCCN)c1ccc2C(=O)NNC(=O)c2c1

InChI

1S/C14H20N4O2/c1-2-18(8-4-3-7-15)10-5-6-11-12(9-10)14(20)17-16-13(11)19/h5-6,9H,2-4,7-8,15H2,1H3,(H,16,19)(H,17,20)

InChI key

LEOJISUPFSWNMA-UHFFFAOYSA-N

Features and Benefits

Efficient chemiluminescent NH2-coupling reagent for detection of a wide variety of proteins down to the picomole range.

Other Notes

Reportedly, the use of this material in chemiluminescent assays has distinct advantages over conventional radioimmunoassay.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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O M Steijger et al.
Journal of chromatography, 615(1), 97-110 (1993-05-19)
N-(4-Aminobutyl)-N-ethylisoluminol was used for labelling of carboxylic acids. The derivatization reaction was carried out with 1-hydroxybenzotriazole as pre-activator of the carboxylic acid function and N-ethyl-N'-(3-dimethylaminopropyl)carbodiimide as the coupling reagent. Optimum conditions for the derivatization were determined by using factorial design
R M Lequin et al.
Journal of immunoassay, 7(3), 169-179 (1986-01-01)
Chemiluminescent labels have been shown to be interesting alternatives to radioisotope labels. Disadvantages of the latter are preparation of e.g. labelled protein/peptides every four to six weeks, and problems with storage and disposal. Amino-Butyl-Ethyl-Isoluminol(ABEI) was attached to the alpha-amino function
Shulin Zhao et al.
Chemical communications (Cambridge, England), 48(5), 699-701 (2011-12-03)
We report on a novel strategy to improve microfluidic immunoassay sensitivity by introducing chemiluminescence resonance energy transfer (CRET) into the immunoreactions. The proposed CRET-based immunoassay for estradiol (E2, as a model analyte) is one of the most sensitive immunoassay with



Global Trade Item Number

SKUGTIN
A0156-250MG04061833326961
A0156-25MG04061833326978