A8082
Antifoam O-30
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About This Item
UNSPSC Code:
12161901
form
emulsion (aqueous)
Quality Level
concentration
100% (organic)
technique(s)
cell culture | hybridoma: suitable, microbiological culture: suitable
density
0.98 g/mL at 25 °C
storage temp.
room temp
suitability
bacteria (fermentation)
Other Notes
A long-lasting fatty acid ester antifoam, 100% active.
Disclaimer
Can be autoclaved repeatedly.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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[The application of antifoam silicones in the microbiological fermentation technic].
L Zalay et al.
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale, 197(1), 118-126 (1965-07-01)
S Zhang et al.
Journal of biotechnology, 25(3), 289-306 (1992-09-01)
Foam formation and the subsequent cell damage/losses in the foam layer were found to be the major problems affecting cell growth and monoclonal antibody (MAb) production in stirred and sparged bioreactors for both serum-supplemented and serum-free media. Surfactants in the
L A van der Pol et al.
Biotechnology progress, 9(5), 504-509 (1993-09-01)
Addition of high concentrations of silicone antifoam (AF) to a suspension of hybridoma cells in a bubble column reduces the death rate when using medium without a protective component. In contrast, high AF concentrations can cause detrimental effects in a