Skip to Content
Merck
CN

A8185

Ala-Gln

BioReagent, suitable for cell culture, suitable for insect cell culture

Synonym(s):

Alanyl-glutamine, Glutamine-S

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C8H15N3O4
CAS Number:
Molecular Weight:
217.22
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.75
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


product line

BioReagent

Quality Level

assay

≥98% (HPLC)

form

powder

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

color

white to off-white

storage temp.

room temp

SMILES string

NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O

InChI

1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1

InChI key

HJCMDXDYPOUFDY-WHFBIAKZSA-N

Application

Ala-Gln has been used:
  • as a supplement in NeuralQ medium
  • as a component in growth medium and incubation medium (IM) for retinal cell lines
  • for experimental treatment of retinal cell lines respectively

Biochem/physiol Actions

Alanyl-glutamine (Ala-Gln) is a dipeptide that is used as a substitute for glutamine in mammalian cell culture media, because of the instability of glutamine in solution and the formation of ammonia as a breakdown product of glutamine in solution, which can have deleterious effects on cells in culture. Ala-Glu is stable to heat sterilization and is less ammonia genic than glutamine, which contributes to its advantages as a media component. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro.

Analysis Note

This product is cell culture tested (0.5 mg/ml) and insect cell culture tested (0.2 mg/ml). It is appropriate for use in cell culture and insect cell culture applications at 2-10 mM.

Legal Information

NeuralQ is a trademark of GlobalStem


Still not finding the right product?

Explore all of our products under Ala-Gln


Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library


Protocols

产生人诱导多能干细胞(iPSC)的干细胞重编程实验方案,包括基于病毒和非病毒RNA的方法。

Stem cell reprogramming protocols to generate human induced pluripotent stem cells (iPSCs) including viral and non-viral RNA based methods.

Articles

PLTMax® Human Platelet Lysate (hPL) is a superior serum-free and xeno-free media supplement alternative to fetal bovine serum (FBS) for human mesenchymal stem cell (MSC) cultures.


Vinicius Fernandes Cruzat et al.
Nutrition (Burbank, Los Angeles County, Calif.), 25(4), 428-435 (2008-12-06)
We investigated the effect of supplementation with the dipeptide L-alanyl-L-glutamine (DIP) and a solution containing L-glutamine and L-alanine, both in the free form, on the plasma and tissue concentrations of glutamine, glutamate, and glutathione (GSH) in rats subjected to long-duration
A high-throughput assay for mRNA silencing in primary cortical neurons in vitro with oligonucleotide therapeutics
Alterman JF, et al.
Bio-protocol, 7(16) (2017)
The adaptation of BHK cells to a non-ammoniagenic glutamate-based culture medium
Christie A, et al.
Biotechnology and Bioengineering, 64(3), 298-309 (1999)



Global Trade Item Number

SKUGTIN
A8185-1KG04061833391273
A8185-100G04061833391266
A8185-5G04061835568093