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A9165

N-Acetyl-L-cysteine

Name: <I>N</I>-Acetyl-<SC>L</SC>-cysteine
Brand: SIGMA

≥99% (TLC), suitable for cell culture, BioReagent

Synonym(s):

LNAC, NAC

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About This Item

Linear Formula:

HSCH₂CH(NHCOCH₃)CO₂H

CAS Number:

616-91-1

Molecular Weight:

163.19

NACRES:

NA.26

PubChem Substance ID:

24891402

UNSPSC Code:

12352209

EC Number:

210-498-3

MDL number:

MFCD00004880

Beilstein/REAXYS Number:

1724426

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Properties

Product Name

N-Acetyl-L-cysteine, suitable for cell culture, BioReagent

product line

BioReagent

Quality Level

200

assay

≥99% (TLC)

form

powder

technique(s)

cell culture | mammalian: suitable

color

white to off-white

mp

106-108 °C (lit.)

solubility

H₂O: 100 mg/mL (with heating)

storage temp.

2-8°C

SMILES string

CC(=O)N[C@@H](CS)C(O)=O

InChI

1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

InChI key

PWKSKIMOESPYIA-BYPYZUCNSA-N

Description

Application

N-Acetyl-L-cysteine has been used as a component of intestinal basal medium for the culture of mouse intestinal stem cells and also as a component of expansion medium.

Biochem/physiol Actions

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.