biological source
plant (white russett potato)
form
lyophilized powder
potency
1.1-6.0 nM Ki [CPB], 1.5-3.5 nM Ki [CPA]
mol wt
apparent mol wt 4.075-4.333 kDa
composition
Protein, ≥35% Lowry
solubility
water: soluble 5 mg/mL, clear
storage temp.
−20°C
Biochem/physiol Actions
Broad-spectrum inhibitor of carboxypeptidases of animal digestive-tract origin, but little or no activity against plant and microbial carboxypeptidases. However, recent results suggest it may play a part in resistance to microbial pathogens by preventing digestion of protein.
Packaging
Package size based on protein content
Physical form
Lyophilized powder containing traces of sodium citrate and sodium chloride; balance primarily non-protein components.
Other Notes
One μg of inhibitor protein will inhibit the activity of ≥3 μg of carboxypeptidase A by 50% using hippuryl-L-phenylalanine as substrate at pH 7.5 at 25°C.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
低风险生物材料
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Related Content
Jarosław Króliczewski et al.
Scientific reports, 6, 34557-34557 (2016-10-05)
The cytochrome b
Purification and properties of a carboxypeptidase inhibitor from potatoes.
C A Ryan et al.
The Journal of biological chemistry, 249(17), 5495-5499 (1974-09-10)
David Thompson et al.
The Journal of biological chemistry, 284(37), 24891-24903 (2009-07-11)
We have identified, purified, and characterized three subcomplexes of PA700, the 19 S regulatory complex of the 26 S proteasome. These subcomplexes (denoted PS-1, PS-2, and PS-3) collectively account for all subunits present in purified PA700 but contain no overlapping
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C0279-10MG | 04061833450390 |
| C0279-25MG | 04061833269312 |
| C0279-5MG | 04061833269329 |