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D4913

2′-Deoxycytidine 5′-triphosphate disodium salt

Name: 2′-Deoxycytidine 5′-triphosphate disodium salt
Brand: SIGMA

100 mM (pH 7)

Synonym(s):

2′-Deoxycytidine-5′-triphosphoric acid disodium salt, dCTP-Na₂

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About This Item

Empirical Formula (Hill Notation):

C₉H₁₄N₃Na₂O₁₃P₃

CAS Number:

102783-51-7

Molecular Weight:

511.12

NACRES:

NA.52

PubChem Substance ID:

24893907

UNSPSC Code:

41106305

MDL number:

MFCD00084683

Assay:

≥99%

Biological source:

synthetic (organic)

Form:

liquid

Storage temp.:

−20°C

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Properties

biological source

synthetic (organic)

Quality Level

200

assay

≥99%

form

liquid

concentration

100 mM (pH 7)

color

colorless

foreign activity

DNase, RNase, none detected

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)O2

InChI

1S/C9H16N3O13P3.2Na/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17);;/q;2*+1/p-2/t5-,6+,8+;;/m0../s1

InChI key

ABWVCNMFYVEBIB-CDNBRZBRSA-L

Description

General description

2′-Deoxycytidine 5′-triphosphate (dCTP) is a cytidine analog. It is composed of a nucleobase attached to deoxyribose and a 5′-hydroxyl on the sugar bound to a chain of three phosphate residues. dCTP is utilized by cells for DNA polymerase catalyzed synthesis of DNA.

Application

2′-Deoxycytidine 5′-triphosphate disodium salt has been used:

in reverse transcription polymerase chain reaction (RT -PCR).
to study the mutations in HBB gene via amplification refractory mutation system (ARMS)-PCR
to C-tail the end-repaired DNA

2′-Deoxycytidine 5′-triphosphate disodium salt is one of the nucleoside triphosphates used for DNA polymerase driven reactions such as polymerase chain reaction, DNA sequencing and other molecular biology methods.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV-1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine.

Nicole Bertoletti et al.

Protein science : a publication of the Protein Society, 28(9), 1664-1675 (2019-07-14)

The retrovirus HIV-1 has been a major health issue since its discovery in the early 80s. In 2017, over 37 million people were infected with HIV-1, of which 1.8 million were new infections that year. Currently, the most successful treatment

Sambrook, J., et al.

Molecular Cloning: A Laboratory Manual, C-C (1989)

Global Trade Item Number

SKU	GTIN
D4913-.1MMO	04061833451021
D4913-25UMO	04061833585870

Key Documents

2′-Deoxycytidine 5′-triphosphate disodium salt

100 mM (pH 7)

Select a Size

About This Item

biological source

Quality Level

assay

form

concentration

color

foreign activity

shipped in

storage temp.

SMILES string

InChI

InChI key

General description

Application

Still not finding the right product?

Safety Information

Storage Class

wgk

flash_point_f

flash_point_c

ppe

Documentation

Certificates of Analysis (COA)

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Peer Reviewed Papers

Global Trade Item Number