D7250
2′-Deoxycytidine 5′-diphosphate sodium salt
≥96%, powder
Synonym(s):
dCDP
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About This Item
Empirical Formula (Hill Notation):
C9H15N3O10P2 · xNa+
CAS Number:
Molecular Weight:
387.18 (free acid basis)
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
MDL number:
Assay:
≥96%
Form:
powder
Storage temp.:
−20°C
Product Name
2′-Deoxycytidine 5′-diphosphate sodium salt, ≥96%
Quality Level
assay
≥96%
form
powder
storage temp.
−20°C
SMILES string
O.[Na].NC1=NC(=O)N(C=C1)C2CC(O)C(COP(O)(=O)OP(O)(O)=O)O2
InChI
1S/C9H15N3O10P2.Na.H2O.H/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(21-8)4-20-24(18,19)22-23(15,16)17;;;/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H2,10,11,14)(H2,15,16,17);;1H2;
InChI key
MNOALMYIRLFAQW-UHFFFAOYSA-N
Application
2′-Deoxycytidine 5′-diphosphate (dCDP) has been used as a substrate for nucleotide diphosphate kinase (NDPK) to produce 2′-deoxycytidine 5′-triphosphate (dCTP) in support of DNA biosynthesis and reverse transcription.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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High glucose triggers nucleotide imbalance through O-GlcNAcylation of key enzymes and induces KRAS mutation in pancreatic cells
Hu CM, et al.
Cell Metabolism, 29(6), 1334-1349 (2019)
Argirios Siskos et al.
Journal of plant physiology, 167(9), 675-682 (2010-03-02)
Two isoforms of NDPKs (diphosphonucleoside kinases: E.C. 2.7.4.6.) named S-NDPK-A and S-NDPK-B were separated and purified from shoots of Alyssum murale (19th day of growth), a nickel accumulator plant, by a four-step procedure involving ammonium sulphate precipitation and DEAE-sepharose and
Hüseyin Besir et al.
FEBS letters, 579(29), 6595-6600 (2005-11-19)
Nucleoside diphosphate kinase from the halophilic archaeon Halobacterium salinarum was crystallized in a free state and a substrate-bound form with CDP. The structures were solved to a resolution of 2.35 and 2.2A, respectively. Crystals with the apo-form were obtained with
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D7250-25MG | 04061833006979 |
| D7250-5MG | 04061833006986 |