D8008
7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid
≥95%
Synonym(s):
DEDA
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About This Item
Empirical Formula (Hill Notation):
C22H40O2
CAS Number:
Molecular Weight:
336.55
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
biological source
synthetic (organic)
assay
≥95%
form
liquid
storage temp.
−20°C
SMILES string
CCCCCCCCCCC\C=C/C(C)(C)\C=C/CCCC(O)=O
InChI
1S/C22H40O2/c1-4-5-6-7-8-9-10-11-12-13-16-19-22(2,3)20-17-14-15-18-21(23)24/h16-17,19-20H,4-15,18H2,1-3H3,(H,23,24)/b19-16-,20-17-
InChI key
AGKRHAILCPYNFH-DUQSFWPASA-N
Gene Information
human ... ADORA2A(135), ADORA2B(136)
Biochem/physiol Actions
Inhibitor of phospholipase A2 and lipoxygenase. Inhibits endogenous synthesis of leukotrienes.
Storage Class
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Thomas L Williams et al.
Langmuir : the ACS journal of surfaces and colloids, 22(15), 6473-6476 (2006-07-13)
This letter describes a new method for studying the interaction of the membrane-lysing enzyme phospholipase A(2) (PLA(2)) with phospholipid bilayers by simultaneous measurements of enzyme binding and vesicle lysis using surface plasmon resonance (SPR) and permeabilization using surface plasmon field-enhanced
Espen Mariussen et al.
Toxicology and applied pharmacology, 179(3), 137-144 (2002-03-22)
Polychlorinated biphenyls (PCBs) are widespread persistent environmental contaminants that display a complex spectrum of toxicological properties, including neurotoxicity. The present study investigates the effects of the PCB mixtures Aroclor 1242 (A1242) and Aroclor 1254 (A1254), and the PCB congeners 126
S Huang et al.
Kidney international, 55(5), 1740-1749 (1999-05-07)
We have studied interleukin-1 (IL-1)-stimulated signals and gene expression in mesangial cells (MCs) to identify molecular mechanisms of MC activation, a process characteristic of glomerular inflammation. The JNK1 pathway has been implicated in cell fate decisions, and IL-1 stimulates the