F2756
Fluorescein di(β-D-galactopyranoside)
Synonym(s):
FDG
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About This Item
Empirical Formula (Hill Notation):
C32H32O15
CAS Number:
Molecular Weight:
656.59
NACRES:
NC.07
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
assay
≥98% (HPLC)
Quality Level
form
powder
solubility
methanol: 20 mg/mL, clear, yellow
storage temp.
−20°C
SMILES string
OC[C@H]1O[C@@H](Oc2ccc3c(Oc4cc(O[C@@H]5O[C@H](CO)[C@H](O)[C@H](O)[C@H]5O)ccc4C36OC(=O)c7ccccc67)c2)[C@H](O)[C@@H](O)[C@H]1O
InChI
1S/C32H32O15/c33-11-21-23(35)25(37)27(39)30(45-21)42-13-5-7-17-19(9-13)44-20-10-14(43-31-28(40)26(38)24(36)22(12-34)46-31)6-8-18(20)32(17)16-4-2-1-3-15(16)29(41)47-32/h1-10,21-28,30-31,33-40H,11-12H2/t21-,22-,23+,24+,25+,26+,27-,28-,30-,31-/m1/s1
InChI key
ZTOBILYWTYHOJB-WBCGDKOGSA-N
General description
Fluorogenic substrate for β-galactosidase
Application
Fluorescein di(β-D-galactopyranoside) has been used as a substrate in β-galactosidase assay.
Fluorescein di(β-D-galactopyranoside) (FDG) has been used for the detection of gene expression via FACS (fluorescence-activated cell sorting).
Biochem/physiol Actions
Fluorescein di (β-D-galactopyranoside) (FDG) results in fluorescence after being hydrolyzed to fluorescein by β-galactosidase. It gives fluorescence proportional to the enzymatic activity. This molecule is mainly required for the detection of gene expression in transfected cells when using β-galactosidase (Lac Z) as a reporter gene.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
涉药品监管产品
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Wei-Heong Tan et al.
Lab on a chip, 6(6), 757-763 (2006-06-02)
This paper describes an electrofusion device for controlling the precise moment of fusion between droplets by applying an electric field. This device allows (i) accurate determination of the start of chemical/biological reactions, (ii) minimum contact of reactants with channel walls--eliminating
Serge A Mitelman et al.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 21(5), 368-382 (2019-09-26)
Objectives: Overlapping decreases in extrastriatal dopamine D2/D3-receptor availability and glucose metabolism have been reported in subjects with schizophrenia. It remains unknown whether these findings are physiologically related or coincidental.Methods: To ascertain this, we used two consecutive 18F-fluorodeoxyglucose and 18F-fallypride positron
Shotaro Naganawa et al.
Medicine, 96(46), e8832-e8832 (2017-11-18)
Although delayed-time-point imaging is expected to improve the results of [F]-fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT), how examinees will benefit from dual-time-point imaging versus initial-time-point imaging alone, remains unclear. This study investigated the role of delayed-time-point imaging in improving the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| F2756-1MG | 04061833613009 |
| F2756-25MG | 04061833613269 |
| F2756-5MG | 04061833613290 |