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Merck
CN

G1029

Monoclonal Anti-Granulocyte Colony Stimulating Factor antibody produced in mouse

clone 3316, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-G-CSF

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43
MDL number:
Conjugate:
unconjugated
Clone:
3316, monoclonal
Application:
ELISA (c), Neutral
Citations:
6
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

3316, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

capture ELISA: suitable, neutralization: suitable

isotype

IgG1

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CSF3(1440)

Immunogen

recombinant human granulocyte colony stimulating factor.

Biochem/physiol Actions

Mature myeloid cells are derived from bone-marrow derived precursor cells by the activity of three colony stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF). The expression of G-CSF is the result of activation of pathways in response to tumor necrosis factor-α, LPS and toll-like receptor ligands. The main functions of G-CSF include the generation of neutrophils and induction of the circulation of hematopoietic stem cells from the bone marrow.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Preparation Note

Purified using protein G.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
低风险生物材料

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H Nagata et al.
The American journal of physiology, 271(6 Pt 1), G1028-G1033 (1996-12-01)
Topical application of ethanol to the gastrointestinal mucosa induces vasodilation. Using an in vivo microscopy technique, we studied the effect of topical ethanol on the submucosal microvessels that control mucosal blood flow in the rat stomach and identified vasoactive substances
R R Ji et al.
Nature neuroscience, 2(12), 1114-1119 (1999-11-26)
We investigated the involvement of extracellular signal-regulated protein kinases (ERK) within spinal neurons in producing pain hypersensitivity. Within a minute of an intense noxious peripheral or C-fiber electrical stimulus, many phosphoERK-positive neurons were observed, most predominantly in lamina I and
Sebastian Stösser et al.
Journal of molecular medicine (Berlin, Germany), 89(4), 321-329 (2010-11-17)
A variety of cancers are accompanied by debilitating pain, which constitutes the primary reason for poor quality of life in cancer patients. There is an urgent demand for the development of specific mechanism-based therapies against cancer pain. Recently, important advances



Global Trade Item Number

SKUGTIN
G1029-500UG04061833624883