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Merck
CN

G8769

D-(+)-Glucose solution

45% in H2O, sterile-filtered, BioXtra, suitable for cell culture

Synonym(s):

D-Glucopyranose

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
NACRES:
NA.75
EC Number:
200-075-1
Beilstein/REAXYS Number:
1281608
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sterility

sterile-filtered

product line

BioXtra

form

solution

concentration

45% in H2O

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

General description

Glucose is the energy currency essential for physiological processes in the living cells. It serves as a precursor for glycoproteins, glycolipids and glycosaminoglycans.

Application

D-(+)-Glucose solution has been used as a medium supplement:
  • in Dulbecco′s Modified Eagle Medium (DMEM) for culturing Flp-In  293 cells
  • in dissection medium for coronal slices from rat brain
  • in neurobasal medium for culturing hippocampi cells

Provides the primary energy source for cell metabolism.

Biochem/physiol Actions

Glucose is a crucial component for the growth and maintenance of mammalian cells in in vitro conditions and is essential for productivity and quality. Its high metabolic turnover favors osteoclast differentiation. The levels of glucose modulate the migration and growth of tumor cells. HeLa cells display high mobility at low glucose levels.


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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Investigation of the Influence of Glucose Concentration on Cancer Cells by Using a Microfluidic Gradient Generator without the Induction of Large Shear Stress
Ishida T, et al.
Micromachines, 7(9), 155-155 (2016)
Protein kinase C activation causes neurite retraction via cyclin D 1 and p60-katanin increase in rat hippocampal neurons
Korulu S, et al.
The European Journal of Neuroscience, 37(10), 1610-1619 (2013)
An ex vivo method for evaluating the biocompatibility of neural electrodes in rat brain slice cultures
Koeneman BA, et al.
Journal of Neuroscience Methods, 137(2), 257-263 (2004)



Global Trade Item Number

SKUGTIN
G8769-100ML04061833649787