H2508
Hippuryl-Arg
carboxypeptidase substrate, chromogenic, ≥98% (TLC), powder
Synonym(s):
N-Benzoyl-Gly-Arg
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C15H21N5O4
CAS Number:
Molecular Weight:
335.36
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
212-015-1
MDL number:
Product Name
Hippuryl-Arg, carboxypeptidase substrate
Quality Level
assay
≥98% (TLC)
form
powder
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
SMILES string
NC(=N)NCCC[C@H](NC(=O)CNC(=O)c1ccccc1)C(O)=O
InChI
1S/C15H21N5O4/c16-15(17)18-8-4-7-11(14(23)24)20-12(21)9-19-13(22)10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,19,22)(H,20,21)(H,23,24)(H4,16,17,18)/t11-/m0/s1
InChI key
GFLCPYUSPYXNBV-NSHDSACASA-N
General description
Substrate for carboxypeptidase B and carboxypeptidase N.
Application
Hippuryl-Arg has been used as a substrate for:
- aminopeptidase from Trogoderma granarium
- exopeptidase from Bactrocera oleae Gmelin, midgut of Plagiodera versicolora
- carboxypeptidase from Pichia pastoris
Biochem/physiol Actions
Hippuryl-Arg is a synthetic substrate for carboxypeptidase B, and aminopeptidase. The enzyme carboxypeptidase acts on C terminal of arginine and lysine.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Hidefumi Komura et al.
Microbiology and immunology, 46(2), 115-117 (2002-04-10)
Carboxypeptidases (CP) in plasma and sera serve as regulators of anaphylatoxins such as C3a and C5a. The activity of CP can be measured by determining hippuric acid after cleavage of the small synthetic substrate hippuryl-L-arginine. Although a colorimetric assay is
Expression, purification and characterization of porcine pancreatic Carboxypeptidase B from Pichia pastoris for the conversion of recombinant human insulin
Mansur M, et al.
Enzyme and Microbial Technology, 40(3), 476-480 (2007)
H Schweisfurth et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 21(10), 605-609 (1983-10-01)
Kininase I (carboxypeptidase N; EC 3.4.17.3) consists of carboxypeptidase N1 (CN1) and carboxypeptidase N2 (CN2); these two enzymes can be differentiated by their activities towards hippuryl-L-arginine and hippuryl-L-lysine, respectively. A spectrophotometric assay for both carboxypeptidases in human serum is described
Global Trade Item Number
| SKU | GTIN |
|---|---|
| H2508-1G | 04061833792216 |
| H2508-100MG | 04061833792209 |
| H2508-250MG | 04061833792223 |
| H2508-500MG | 04061832917580 |