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M1633

4-Methylumbelliferyl β-D-galactopyranoside

fluorogenic, ≥99% (TLC), powder

Synonym(s):

MUG, MUGA

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About This Item

Empirical Formula (Hill Notation):
C16H18O8
CAS Number:
Molecular Weight:
338.31
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
228-185-5
MDL number:
Beilstein/REAXYS Number:
94673
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Product Name

4-Methylumbelliferyl β-D-galactopyranoside, ≥99% (TLC)

Quality Level

assay

≥99% (TLC)

form

powder

solubility

pyridine: 10 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

CC1=CC(=O)Oc2cc(O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)ccc12

InChI

1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13+,14+,15-,16-/m1/s1

InChI key

YUDPTGPSBJVHCN-DZQJYWQESA-N

General description

4-Methylumbelliferyl β-D-galactopyranoside (MUG) is a UV-absorbing dye that serves as a fluorescent substrate for β-galactosidase in a planar yeast estrogen screen (pYES) for the detection of estrogen active compounds.

Application

4-Methylumbelliferyl β-D-galactopyranoside has been used as a substrate in β-galactosidase activity assay.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Maura Samarani et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(10), 5685-5702 (2018-05-11)
Lysosomal accumulation of undegraded materials is a common feature of lysosomal storage diseases, neurodegenerative disorders, and the aging process. To better understand the role of lysosomal storage in the onset of cell damage, we used human fibroblasts loaded with sucrose
Misbaudeen Abdul-Hammed et al.
Journal of lipid research, 58(3), 563-577 (2017-01-28)
Glucosylceramide (GlcCer) is the primary storage lipid in the lysosomes of Gaucher patients and a secondary one in Niemann-Pick disease types A, B, and C. The regulatory roles of lipids on the hydrolysis of membrane bound GlcCer by lysosomal β-glucocerebrosidase
Zaijie Chen et al.
Frontiers in plant science, 8, 1447-1447 (2017-09-06)
Inducible gene expression has emerged as a powerful tool for plant functional genomics. The estrogen receptor-based, chemical-inducible system XVE has been used in many plant species, but the limited systemic movement of inducer β-estradiol in transgenic rice plants has prohibited



Global Trade Item Number

SKUGTIN
M1633-5G04061832909110
M1633-1G04061835512737
M1633-250MG04061834040972