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Merck
CN

MAK109

LPL Activity Assay Kit

Supplied by Roar Biomedical, Inc.

Synonym(s):

Lipoprotein lipase activity assay kit

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About This Item

NACRES:
NA.84
UNSPSC Code:
12161503
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usage

sufficient for 100 fluorometric tests

application(s)

pharmaceutical

detection method

fluorometric

relevant disease(s)

gastrointestinal diseases; cardiovascular diseases

storage temp.

2-8°C

Gene Information

human ... LPL(4023)

General description

Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.

Application

LPL Activity Assay Kit may be used for detection of LPL activity in plasma samples of patients with hypertriglyceridemia.
Suitable for the measurement of lipoprotein lipase activity in a variety of tissue samples

Biochem/physiol Actions

The LPL Activity Assay Kit includes a non-fluorescent substrate emulsion that becomes intensely fluorescent upon interaction with LPL and pre-hydrolyzed substrate for use as a standard to convert the fluorescence intensity reading to moles of reactant formed (λEx=370 nm/λEm=450 nm). The assay is not specific for LPL and will also detect hepatic lipase activity.


Storage Class

10 - Combustible liquids



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Protocols

Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.


Chaofeng Yang et al.
Nutrition & metabolism, 9(1), 94-94 (2012-10-31)
Endocrine FGF19 and FGF21 exert their effects on metabolic homeostasis through fibroblast growth factor receptor (FGFR) and co-factor betaKlotho (KLB). Ileal FGF19 regulates bile acid metabolism through specifically FGFR4-KLB in hepatocytes where FGFR1 is not significant. Both FGF19 and FGF21
Tomomi Yamazaki et al.
Journal of lipid research, 53(10), 2024-2037 (2012-06-28)
Postprandial hyperlipidemia (lipemia) is a risk factor for atherosclerosis. However, mouse models of postprandial hyperlipidemia have not been reported. Here, we report that ddY mice display marked postprandial hypertriglyceridemia in response to dietary fat. In ddY mice, the fasting serum
Ismayil Tasdelen et al.
PloS one, 8(5), e64284-e64284 (2013-05-23)
The transcription factor PPARγ is the key regulator of adipocyte differentiation, function and maintenance, and the cellular target of the insulin-sensitizing thiazolidinediones. Identification and functional characterization of genes regulated by PPARγ will therefore lead to a better understanding of adipocyte



Global Trade Item Number

SKUGTIN
MAK109-1KT04061834065340