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Merck
CN

P1406

Protein A–Agarose

lyophilized powder

Synonym(s):

Protein A resin

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About This Item

UNSPSC Code:
41106500
NACRES:
NA.56
MDL number:
Form:
lyophilized powder
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form

lyophilized powder

Quality Level

extent of labeling

~2 mg per mL

matrix

Cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

capacity

≥15 mg/mL binding capacity (human IgG)

storage temp.

−20°C

Application

Protein A-agarose is used for affinity chromatography, antibody purification and characterization, and protein A, G and L resins. Protein A-agarose has been used to study the effects of protein A immunoadsorption in patients with chronic dilated cardiomyopathy as well as to study multiple sclerosis and gastric cancer. Protein A–Agarose has been used as an immobilized biosensor. It has also been used for immunoprecipitation.

Physical form

Supplied as lyophilized powder stabilized with lactose.

Preparation Note

Swelling: 1 g swells to 3-6 ml


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pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

常规特殊物品

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Fredrik Fagerström-Billai et al.
Molecular and cellular biology, 25(2), 716-727 (2005-01-06)
Gene duplication is considered an important evolutionary mechanism. Unlike many characterized species, the fission yeast Schizosaccharomyces pombe contains two paralogous genes, tup11+ and tup12+, that encode transcriptional corepressors similar to the well-characterized budding yeast Tup1 protein. Previous reports have suggested
Z Chen et al.
Circulation research, 82(3), 367-374 (1998-03-05)
Phospholemman (PLM) is a small (72-amino acid) transmembrane protein found in cardiac sarcolemma that is a major substrate for several protein kinases in vivo. Detailed structural data for PLM is lacking, but several studies have described an ion conductance that
L G Reddy et al.
The Journal of biological chemistry, 270(16), 9390-9397 (1995-04-21)
Phospholamban (PLB) is a small, transmembrane protein that resides in the cardiac sarcoplasmic reticulum (SR) and regulates the activity of Ca(2+)-ATPase in response to beta-adrenergic stimulation. We have used the baculovirus expression system in Sf21 cells to express milligram quantities



Global Trade Item Number

SKUGTIN
P1406-1G04061834354826
P1406-1.5G04061834354796
P1406-250MG04061834354857
P1406-5G04061834354901