P5648
β-Propiolactone
Grade II, ≥90%
Synonym(s):
Oxetan-2-one, 3-Hydroxypropionic acid lactone, Hydracrylic acid β-lactone
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About This Item
Empirical Formula (Hill Notation):
C3H4O2
CAS Number:
Molecular Weight:
72.06
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352103
EC Number:
200-340-1
MDL number:
Assay:
≥90%
Quality level:
type
Grade II
Quality Level
assay
≥90%
refractive index
n20/D 1.412 (lit.)
bp
162 °C (lit.)
mp
−33 °C (lit.)
density
1.146 g/mL at 25 °C (lit.)
storage temp.
−20°C
SMILES string
O=C1CCO1
InChI
1S/C3H4O2/c4-3-1-2-5-3/h1-2H2
InChI key
VEZXCJBBBCKRPI-UHFFFAOYSA-N
General description
β-Propiolactone is an alkylating agent which is mainly used in veterinary vaccines. It will not interfere with the antigenicity of vaccine.
Application
β-Propiolactone has been used for Influenza virus deactivation.
Disclaimer
Insoluble polymers may form during storage.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
158.0 °F - closed cup
flash_point_c
70 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Regulatory Information
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Vesla I Kullaya et al.
Viral immunology, 30(8), 576-581 (2017-08-08)
Detection of respiratory syncytial virus (RSV) in blood, including mononuclear leukocytes and organs other than the lung, suggests that RSV disseminates outside the respiratory tract. In this study, the role of platelets in host defense against RSV was explored using
Veterinary Immunology-E book, 262-262 (2013)
Wei Zhang et al.
Viruses, 11(7) (2019-07-11)
To date, there is no licensed vaccine available to prevent respiratory syncytial virus (RSV) infection. The valuable pre-fusion conformation of the fusion protein (pre-F) is prone to lose high neutralizing antigenic sites. The goals of this study were to stabilize
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P5648-10ML | 04061838164629 |
| P5648-100ML | 04061838164612 |
| P5648-1ML | 04061838164636 |
| P5648-50ML | 04061838114556 |
| P5648-5ML | 04061838092823 |