SAE0073
Saponin
Synonym(s):
Surfactant Saponin
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About This Item
UNSPSC Code:
12161902
EC Number:
232-462-6
NACRES:
NA.21
description
non-ionic
Quality Level
composition
Sapogenin content, 20-35%
technique(s)
HPLC: suitable, LC/MS: suitable, protein quantification: suitable
sulfated ash
≤10%
Application
Saponins has been used to permeabilize dendritic cells (DCs) for intracellular staining with antibodies.
Biochem/physiol Actions
Saponins are associated with many biological and pharmacological activities. It is known to stimulate immune response in mammals. Saponins possesses antiviral, antifungal, antitumor, anti-inflammatory, hypoglycemic and hypocholesterolemic effects. It is a potent hemolytic, when injected intravaneously. It is also useful as a surfactant to enhance penetration of proteins and other macromolecules through cell membranes. Saponins have also been used as adjuvants for vaccines.
Packaging
10, 25 g in poly bottle
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Flavia Radogna et al.
Methods in molecular biology (Clifton, N.J.), 2276, 129-141 (2021-06-02)
Cellular energy metabolism is regulated by complex metabolic pathways. Although anaerobic glycolysis was reported as a primary source of energy in cancer leading to a high rate of lactate production, current evidence shows that the main energy source supporting cancer
Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation
Gotoh K, et al.
Cell Reports, 25(7), 1800-1815 (2018)
Advances in saponin-based adjuvants
Sun HX, et al.
Vaccine, 27(12), 1787-1796 (2009)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAE0073-25G | 04061833493458 |
| SAE0073-10G | 04061833343395 |