SH0831
MISSION® shRNA Human Gene Family Set, Lentiviral Particles
Cytokines and Chemokines
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
NACRES:
NA.51
UNSPSC Code:
41106609
General description
Lentiviral particles (representational, plate titer) are provided in 96-well plates that are barcoded for simple identification. Aliquots of 4 x 50μl are provided to prevent the need for excessive freeze/thaw, and maximize functional viral particles. Each gene family set is representationally titered (10% of clones). Fully titered sets are also available, for more information inquire at RNAi@sial.com. A CD containing RefSeq, gene description, gene symbol, clone ID, hairpin sequence, locus link, and plate map positions are provided with the gene family set.
Other Notes
Number of Genes: 106, Number of Clones: 528
The exact gene and clone count at time of purchase may vary slightly as the TRC library is continually updated.
Each MISSION shRNA clone is constructed within the lentivirus plasmid vector, pLKO.1-Puro, followed by transformation into Escherichia coli. The pLKO.1-Puro vector contains bacterial (ampicillin) and mammalian (puromycin) antibiotic resistance genes for selection of inserts in either bacterial or mammalian cell lines. Each clone set consists of an average of 3-5 constructs that have been designed against each target gene using a proprietary algorithm. Therefore, a range of knockdown efficiency, with at least one construct from each gene set being >70%, can be expected when using these clones. This allows one to examine the effect of loss of gene function over a large series of gene knockdown efficiencies. Each shRNA construct has been cloned and sequence verified to ensure a match to the target gene.
For a detailed listing of other available gene family sets, visit the gene family set website.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Use of this product is subject to one or more license agreements. For details, please see http://sigmaaldrich.com/missionlicense .
Still not finding the right product?
Explore all of our products under MISSION® shRNA Human Gene Family Set, Lentiviral Particles
Storage Class
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
低风险生物材料
高风险级别生物产品--病毒，疫苗等
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Related Content
Instructions
Paul Anderson
Nature immunology, 9(4), 353-359 (2008-03-20)
The cytokine-encoding messenger RNA (mRNA) molecules transcribed in the nucleus acquire a protein coat that facilitates nuclear export, influences cytoplasmic localization, and determines stability and translational competence. The composition of this coat is determined by sequence elements that recruit proteins
Vandana Tayal et al.
European journal of pharmacology, 579(1-3), 1-12 (2007-11-21)
Cytokines which comprise of a family of proteins--interleukins, lymphokines, monokines, interferons, and chemokines, are important components of the immune system. They act in concert with specific cytokine inhibitors and soluble cytokine receptors to regulate the human immune response. Their physiologic
The many roles of chemokines and chemokine receptors in inflammation.
Israel F Charo et al.
The New England journal of medicine, 354(6), 610-621 (2006-02-10)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SH0831 | 04061823781121 |