A4685
Luminol sodium salt
luminescent, ≥98% (titration), powder and chunks
Synonym(s):
3-Aminophthalhydrazide, 5-Amino-2,3-dihydro-1,4-phthalazinedione
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About This Item
Linear Formula:
C8H6N3O2Na
CAS Number:
Molecular Weight:
199.14
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83
MDL number:
Product Name
Luminol sodium salt,
assay
≥98% (titration)
Quality Level
form
powder and chunks
solubility
water: 50 mg/mL, clear to very slightly hazy, colorless to faint red
SMILES string
O=C1NN([Na])C(C2=CC=CC(N)=C21)=O
InChI
1S/C8H7N3O2.Na/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12;/h1-3H,(H4,9,10,11,12,13);/q;+1/p-1
InChI key
RVJVDCVIJCBUTH-UHFFFAOYSA-M
Application
Luminol sodium salt has been used:
- as a component of MEBSS buffer in a bioluminescence assay to detect peroxidase activity in whole blood samples
- to study protein interaction in whole-cell lysates by immunoprecipitation
- for in vitro reactive oxygen species (ROS) quantification in CD45+ and CD45− cells
Biochem/physiol Actions
Luminol is a redox-sensitive chemiluminescent compound. It emits blue luminescence when the basic aqueous solution of luminol having oxygen atoms come in contact with oxidizing agents like potassium ferricyanide. It is highly stable and is applicable in various fields such as analytical chemistry, metallurgy, biochemistry, and forensics for detecting reactive species. Luminol has the potential to detect defects in neutrophils ex vivo during oxidative metabolism defects such as chronic granulomatous disease and myeloperoxidase deficiency.
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wgk
WGK 3
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Related Content
New Developments in Chemiluminescence Research
Gill, Steven, K.
Aldrichimica Acta, 16, 59-59 (1983)
Chemiluminescence detection in analytical chemistry
Lancaster, J. Steven
Endeavour, 16, 194-194 (1992)
Luminol Chemiluminescence-Delay Method for Determination of Copper(II)
Kamidate, Tamio; Ishikawa, Atsushi; Watanabe, Hiroto.
Bulletin of the Chemical Society of Japan, 65, 1591-1591 (1992)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A4685-1G | 04061833374931 |
| A4685-25G | 04061833374948 |
| A4685-5G | 04061833374955 |