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Merck
CN

A5633

Antifoam A Concentrate

active silicone polymer 100 %

Synonym(s):

Silicone Antifoam Solution

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About This Item

NACRES:
NA.25
UNSPSC Code:
12161900
Technical Service
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description

100% active silicone polymer

Quality Level

form

suspension

does not contain

emulsifier

composition

active silicone polymer, 100%

technique(s)

cell culture | mammalian: suitable, microbiological culture: suitable

density

(0.97 g/mL at 25 °C (77 °F))

General description

Antifoam A Concentrate is an extremely effective foam suppressor for aqueous and non-aqueous systems. It is 100% active silicone polymer. No emulsifiers are present. Antifoam A Concentrate is typically effective at 1-100 ppm. Antifoam A Concentrate should be diluted with 3-10 parts of propylene glycol (aqueous) or vegetable oil (nonaqueous) with slow mixing. The product will be stable in the pH range of 5 to 9. Antifoam A Concentrate can be added directly to a fermentation medium, but it is not recommended that it be pumped to a fermenter on an as-needed basis.

Application

Antifoam A Concentrate has been used as a component of Luria Bertani culture medium for growth of BL21 (DE3) E. coli cells transformed with the plasmids. It has also been used as a constituent in the preparation of aerosol generation fluid.
An extremely effective foam suppresser for use in aqueous and non-aqueous systems.

Preparation Note

1-50 ppm is adequate for most applications.


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pictograms

Environment

Storage Class

10 - Combustible liquids

flash_point_f

>213.8 °F - closed cup

flash_point_c

> 101 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - PBT - vPvB



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Reduced IFN lambda 4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes
Terczynska DE, et al.
Nature Communications, 5, 5699-5699 (2014)
Interferon lambda 4 signals via the IFN$\lambda$ receptor to regulate antiviral activity against HCV and coronaviruses
Hamming OJ, et al.
The Embo Journal, 32(23), 3055-3065 (2013)
Resistance of aerosolized bacterial viruses to relative humidity and temperature
Verreault D, et al.
Applied and Environmental Microbiology, 81(20), 7305-7311 (2015)



Global Trade Item Number

SKUGTIN
A5633-100G04061833376171
A5633-25G04061833376188