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A7223

Albumin human

recombinant, expressed in Pichia pastoris, 5% in aqueous buffer, ≥90% (SDS-PAGE)

Synonym(s):

Albagen, rHSA

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About This Item

Empirical Formula (Hill Notation):
C2936H4624N786O889S41
CAS Number:
Molecular Weight:
66471.53
UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:
Biological source:
human
Assay:
≥90% (SDS-PAGE)
Form:
solution
Technique(s):
cell culture | mammalian: suitable
Concentration:
5% in aqueous buffer
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biological source

human

Quality Level

recombinant

expressed in Pichia pastoris

assay

≥90% (SDS-PAGE)

form

solution

mol wt

monomer ~67 kDa

concentration

5% in aqueous buffer

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

SMILES string

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Gene Information

human ... ALB(213)

General description

Recombinant construct with N-terminal deletion of Asp. Structurally equivalent to native albumin by x-ray crystallography. The N-terminal Asp is the principal Cu2+ and Ni2+ chelation site; its deletion eliminates an important antigenic determinant, and the protein is hypoallergenic. Also blocked at Cys34 to improve stability, monomer content and homogeneity.

Application

This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.

Biochem/physiol Actions

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Physical form

Solution in phosphate buffered saline containing 4 mM sodium caprylate and 4 mM N-acetyltryptophan.

Other Notes

View more information on human serum albumin.

Legal Information

Albagen is a trademark of Albumin Therapeutics, LLC.


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Global Trade Item Number

SKUGTIN
A7223-1G04061833383834