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About This Item
Empirical Formula (Hill Notation):
C2936H4624N786O889S41
CAS Number:
Molecular Weight:
66471.53
UNSPSC Code:
12352202
eCl@ss:
42010201
NACRES:
NA.25
MDL number:
Biological source:
human
Assay:
≥96% (SDS-PAGE)
Form:
lyophilized powder
Technique(s):
cell culture | mammalian: suitable
Impurities:
≤1 EU/mg protein
biological source
human
recombinant
expressed in rice
assay
≥96% (SDS-PAGE)
form
lyophilized powder
mol wt
monomer ~67 kDa
technique(s)
cell culture | mammalian: suitable
impurities
≤1 EU/mg protein
UniProt accession no.
storage temp.
2-8°C
SMILES string
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
Gene Information
human ... ALB(213)
Application
This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.
Biochem/physiol Actions
Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.
Features and Benefits
Cellastim™ is a well defined, animal-free recombinant human albumin (rHA). Designed for cell culture applications, Cellastim is a powerful media supplement that outperforms plasma-derived human albumin, bovine serum albumin, and other sources of recombinant human albumin. Cellastim delivers consistent performance, not the variability associated with hydrolysates and extracts. Cellastim is ideally suited for use in cell culture media for Chinese Hamster Ovary (CHO), hybridoma, VERO, stem cells and primary cells.
Advantages
Advantages
- Eliminates animal-derived additives
- Safe and regulatory friendly
- Proven effective in enhancing stem cell growth in embryonic, mesenchymal, neural, cardiac, liver, kidney, keratinocyte and fibroblast stem cell lines
- Maintains stem cells in an undifferentiated state
- Eliminates coating of culture plates for adherent cell lines
- Provides well-defined and consistent stem cell medium
Analysis Note
Assayed by SDS-PAGE
Other Notes
1). Patent Rights
EP2230311
U.S. Patent No. 10618951
U.S. Patent No. 10981974
U.S. Patent No. 11492389
2). Registered Trademark Rights
U.S. Reg. 5696531
International Reg. 1456207
EP2230311
U.S. Patent No. 10618951
U.S. Patent No. 10981974
U.S. Patent No. 11492389
2). Registered Trademark Rights
U.S. Reg. 5696531
International Reg. 1456207
To view more information on Cellastim download the Cellastim Brochure, Cellastim CHO Poster, and Cellastim hybridoma Poster.
View more information on human serum albumin.
Legal Information
rHSA manufactured in the USA by InVitria US Pat 10618951, 10981974, and 11492389.
Cellastim is a trademark of InVitria
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
常规特殊物品
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Articles
本页将全面阐述血清白蛋白和其他重要细胞培养成分如何影响用于单克隆抗体等外源蛋白生物制造的无血清细胞培养系统的性能，并介绍白蛋白的体外化学和生物化学过程。本页面将介绍白蛋白在体外化学和生物化学领域的应用。这些深度知识可能也适用于离体和组织工程学应用。
脂肪组织中的胰岛素耐受性减少了循环游离脂肪酸的摄入，并增加了脂肪酶对储存甘油三酯的水解。了解与胰岛素耐受性相关的激素、细胞因子和脂肪因子。
Lipid Induced Insulin Resistance
Junfeng Zhu et al.
Journal of pharmaceutical and biomedical analysis, 134, 100-107 (2016-11-28)
Danhong injection (DHI) is a widely used Chinese medicine injection (CMI) for the clinical treatment of cardiovascular and cerebrovascular diseases. In this study, a simple and efficient in vitro method based on ultrafiltration LC-MS and molecular modeling has been developed
Yongjia Fan et al.
ACS biomaterials science & engineering, 3(8), 1510-1518 (2016-08-14)
The development of platforms for the expansion and directed differentiation of human pluripotent stem cells (hPSCs) in large quantities under xeno-free conditions is a key step toward the realization of envisioned stem cell-based therapies. Microcarrier bioreactors afford great surface-to-volume ratio
D Moreno et al.
Theriogenology, 84(7), 1053-1060 (2015-08-19)
The aim of this study was to develop an in vitro embryo culture medium without either fetal calf serum or BSA, using various growth factors and cytokines (GFs-CYKs; IGF-I, IGF-II, bFGF, LIF, GM-CSF, TGF-β1, and PDGF-BB), and other molecules with
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A9731-10G | 04061833412275 |
| A9731-1G | 04061833412282 |
| A9731-5G | 04061833412299 |