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Merck
CN

F1506

Sodium fumarate dibasic

≥99%

Synonym(s):

Disodium fumarate, Fumaric acid disodium salt

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About This Item

Linear Formula:
NaOOCCH=CHCOONa
CAS Number:
Molecular Weight:
160.04
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
241-087-7
Beilstein/REAXYS Number:
4301302
MDL number:
Assay:
≥99%
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Quality Level

assay

≥99%

SMILES string

[Na+].[Na+].[O-]C(=O)\C=C\C([O-])=O

InChI

1S/C4H4O4.2Na/c5-3(6)1-2-4(7)8;;/h1-2H,(H,5,6)(H,7,8);;/q;2*+1/p-2/b2-1+;;

InChI key

MSJMDZAOKORVFC-SEPHDYHBSA-L

Application

  • Enhancement of drug absorption: Sodium fumarate dibasic is utilized to improve the dissolution behavior and oral absorption of drugs with pH-dependent solubility, enhancing bioavailability and therapeutic efficacy in pharmaceutical applications (Salehi et al., 2021).
  • Development of novel drug carriers: The compound is used in the synthesis and characterization of novel injectable drug carriers, aiming to enhance the delivery and efficacy of therapeutic agents in medical treatment strategies (Guo et al., 2005).


Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Articles

Fatty acid synthesis supports cancer cell proliferation, essential for membrane generation, protein modification, and bioenergetics.


Xueying Liu et al.
Molecules (Basel, Switzerland), 24(12) (2019-06-21)
The major objective of this study was to investigate the anti-chronic nonbacterial prostatitis (CNP) mechanism of T. patula by metabolomics and network pharmacology. The study demonstrated that the flavonoids and polysaccharides of T. patula could alleviate prostatitis by improving the
Yasemin D Yilmazel et al.
Bioelectrochemistry (Amsterdam, Netherlands), 119, 142-149 (2017-10-11)
Few microorganisms have been examined for current generation under thermophilic (40-65°C) or hyperthermophilic temperatures (≥80°C) in microbial electrochemical systems. Two iron-reducing archaea from the family Archaeoglobaceae, Ferroglobus placidus and Geoglobus ahangari, showed electro-active behavior leading to current generation at hyperthermophilic
Carl Roos et al.
Molecular pharmaceutics, 14(12), 4252-4261 (2017-09-19)
Currently, the screening of new drug candidates for intestinal permeation is typically based on in vitro models which give no information regarding regional differences along the gut. When evaluation of intestinal permeability by region is undertaken, two preclinical rat models



Global Trade Item Number

SKUGTIN
F1506-100G-A04061833612002
F1506-100G04061833611999
F1506-25G04061833612033
F1506-500G04061833612071
F1506-500G-A04061832489988
F1506-5G-A04061833612088