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Merck
CN

L7026

Lithium chloride solution

8 M, Molecular Biology, ≥99%

Synonym(s):

LiCl

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About This Item

Linear Formula:
LiCl
CAS Number:
Molecular Weight:
42.39
NACRES:
NA.31
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
eCl@ss:
38050203
Assay:
≥99%
Grade:
Molecular Biology
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grade

Molecular Biology

assay

≥99%

concentration

8 M

anion traces

sulfate (SO42-): ≤0.01%

cation traces

Ba: ≤0.003%, Fe: ≤0.001%, K: ≤0.01%, Na: ≤0.20%, heavy metals (as Pb): ≤0.002%

foreign activity

DNase, RNase, protease, none detected

SMILES string

[Li+].[Cl-]

InChI

1S/ClH.Li/h1H;/q;+1/p-1

InChI key

KWGKDLIKAYFUFQ-UHFFFAOYSA-M

Application

Lithium chloride solution has been used:
  • to obtain LiClPAM3 DCs form of dendritic cell
  • in LiCl buffer preparation for immunoprecipitation
  • in the preparation of wash buffer
  • in the preparation of radioimmunoprecipitation assay (RIPA) wash buffer

May be used to selectively precipitate RNA.

Biochem/physiol Actions

Lithium chloride has the ability to block glycogen synthase kinase (GSK). It may also possess anti-inflammatory effects at low and non-toxic concentrations.

Preparation Note

Prepared with 18 megaohm water
0.2 μm filtered


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Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Articles

了解 mRNA 疫苗如何诱导免疫,以及如何为疫苗免疫原和其他生物制药制备合成 mRNA。寻找合成 mRNA 所需的试剂。

Understand how mRNA vaccines induce immunity. and read how synthetic mRNA is prepared for vaccine immunogens and other biopharmaceuticals. Find reagents for synthesis of mRNA.

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用于质粒制备、体外转录、mRNA 纯化和 LNP 制剂的工具,用于基于 mRNA 的疫苗和疗法开发。

Tools for plasmid preparation, in vitro transcription, mRNA purification, and LNP formulation in mRNA-based vaccine and therapeutic development.


mTOR and neuroinflammation
Molecules to Medicine with mTOR, 317-329 (2016)
Allostimulatory Effects of Dendritic Cells with Characteristic Features of a Regulatory Phenotype
Kouwenberg M, et al.
PLoS ONE, 11(8), e0159986-e0159986 (2016)
RNA Chromatin Immunoprecipitation (RNA-ChIP) in Caenorhabditis elegans
Cecere G and Grishok A
Nature Structural and Molecular Biology (2014)



Global Trade Item Number

SKUGTIN
L7026-100ML04061838820235
L7026-1L04061833965313
L7026-500ML04061833965320