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Merck
CN

109185

糖精

≥98%

别名:

2,3-二羟基-1,2-苯并异噻唑基-3-酮-1,1-二氧化物, 2-磺基苯甲酸亚胺, 邻磺酰苯酰亚胺

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关于此项目

经验公式(希尔记法):
C7H5NO3S
化学文摘社编号:
分子量:
183.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-321-0
Beilstein/REAXYS Number:
6888
MDL number:
Assay:
≥98%
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Quality Level

assay

≥98%

mp

226-229 °C (lit.)

solubility

H2O: soluble 1g in 290ml, acetone: soluble 1g in 12ml, alcohol: soluble 1g in 31ml, boiling water: soluble 1g in 25ml, glycerol: soluble 1g in 50ml, alcohol: very slightly soluble, chloroform: slightly soluble, diethyl ether: slightly soluble

SMILES string

O=C1NS(=O)(=O)c2ccccc12

InChI

1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)

InChI key

CVHZOJJKTDOEJC-UHFFFAOYSA-N

Application

高效液相色谱法采用糖精对乙酰磺胺酸钾、糖精和阿斯巴甜进行同时分离和测定 。用于大鼠的甜味偏好测试

Biochem/physiol Actions

N-甲基-N′-硝基-N-亚硝基胍后给予糖精促进大鼠肿瘤的发展
哺乳动物的甜促味剂。有人提出,果蝇具有葡萄糖特异性甘油味觉受体结合位点。


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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Anne Marie Vinggaard et al.
Toxicological sciences : an official journal of the Society of Toxicology, 85(2), 886-897 (2005-03-25)
Prochloraz is a commonly used fungicide that has shown multiple mechanisms of action in vitro. It antagonizes the androgen and the estrogen receptors, agonizes the Ah receptor, and inhibits aromatase activity. In vivo prochloraz acts antiandrogenically in the Hershberger assay
Simultaneous determination of artificial sweeteners in possible counterfeited wines, using high performance liquid chromatography with DAD detection.
Geana EI, et al.
Analele Universitatii Ovidius din Constanta-Seria Chimie, 23(1), 77-81 (2012)
M Takahashi et al.
Gan, 75(6), 494-501 (1984-06-01)
Sodium chloride, saccharin sodium, phenobarbital sodium and aspirin were tested for tumor-promoting activity in the glandular stomach of rats after initiation with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) coupled with administration of a high salt diet. Male outbred Wistar rats were given MNNG in



全球贸易项目编号

货号GTIN
109185-250G04061835554089
109185-500G04061833544327