Quality Level
assay
98%
form
solid
bp
202-205 °C/105 mmHg (lit.)
mp
71-74 °C (lit.)
functional group
acyl chloride, nitro
SMILES string
[O-][N+](=O)c1ccc(cc1)C(Cl)=O
InChI
1S/C7H4ClNO3/c8-7(10)5-1-3-6(4-2-5)9(11)12/h1-4H
InChI key
SKDHHIUENRGTHK-UHFFFAOYSA-N
General description
对硝基苯甲酰氯与三苯基膦盐反应,通过分子内维蒂希反应合成苯并呋喃(潜在正电子发射断层扫描 (PET) 示踪剂)。它已被用于二醇(雄烯二醇,前列腺癌的内源性增殖剂)的衍生化 。
Application
<ul>
<li><strong>[11C]PiB的自动合成::</strong> 4-硝基苯甲酰氯被用于[11C]PiB的自动合成,[11C]PiB是一种用于淀粉样蛋白PET成像的放射性药物,研究突出了其在增强神经成像技术方面的作用 (Singh et al., 2024)。</li>
</ul>
<li><strong>[11C]PiB的自动合成::</strong> 4-硝基苯甲酰氯被用于[11C]PiB的自动合成,[11C]PiB是一种用于淀粉样蛋白PET成像的放射性药物,研究突出了其在增强神经成像技术方面的作用 (Singh et al., 2024)。</li>
</ul>
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 1
flash_point_f
215.6 °F - closed cup
flash_point_c
102 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Masahiro Ono et al.
Journal of medicinal chemistry, 49(9), 2725-2730 (2006-04-28)
A novel series of benzofuran derivatives as potential positron emission tomography (PET) tracers targeting amyloid plaques in Alzheimer's disease (AD) were synthesized and evaluated. The syntheses of benzofurans were successfully achieved by an intramolecular Wittig reaction between triphenylphosphonium salt and
Tatsuya Higashi et al.
Steroids, 71(11-12), 1007-1013 (2006-09-19)
Androstenediol (Adiol, androst-5-ene-3beta,17beta-diol) is suspected of being an endogenous proliferation agent of prostate cancer (PCa) even after androgen deprivation therapy (ADT). A liquid chromatography-electron capture atmospheric pressure chemical ionization-mass spectrometric (LC-ECAPCI-MS) method for the determination of Adiol in prostatic tissue
M Ishigai et al.
Analytical biochemistry, 298(1), 83-92 (2001-10-25)
The dynamics of enzyme-catalyzed glutathione conjugation was studied by electrospray quadrupole/time-of-flight (Q-TOF) mass spectrometry with a nanospray interface. After incubation of human glutathione S-transferase A1-1 (GT) with glutathione (GSH) and an electrophilic substrate, electrospray indicated the presence of enzyme/product adducts
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 112208-500G | 04061832489117 |
| 112208-250G | 04061835281329 |
| 112208-50G | 04061835281336 |
