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122505

2,3-二羟基吡啶

Name: 2,3-二羟基吡啶
Brand: ALDRICH

95%

别名:

2,3-吡啶二醇

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关于此项目

经验公式（希尔记法）:

C₅H₅NO₂

化学文摘社编号:

16867-04-2

分子量:

111.10

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24847492

EC Number:

240-887-3

Beilstein/REAXYS Number:

109848

MDL number:

MFCD00006271

Assay:

95%

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属性

Quality Level

100

assay

95%

mp

245 °C (dec.) (lit.)

SMILES string

Oc1cccnc1O

InChI

1S/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)

InChI key

GGOZGYRTNQBSSA-UHFFFAOYSA-N

说明

Application

2,3-二羟基吡啶（DHP）用于通过偶氮偶合剂合成DHP负载的Amberlite XAD-2。通过使用连接基团 -NH-CH₂-CH₂-NH-SO₂-C₆H₄-N=N- 和 -SO₂-C₆H₄-N=N将DHP负载在纤维素上，可将DHP用于合成新型大分子螯合剂。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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2, 3-Dihydroxypyridine loaded amberlite XAD-2 (AXAD-2-DHP): preparation, sorption-desorption equilibria with metal ions, and applications in quantitative metal ion enrichment from water, milk and vitamin samples.

Venkatesh G, et al.

Microchimica Acta, 149(3-4), 213-221 (2005)

6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H.

Lei Wang et al.

European journal of medicinal chemistry, 156, 680-691 (2018-07-23)

Human immunodeficiency virus (HIV) reverse transcriptase (RT)-associated ribonuclease H (RNase H) remains an unvalidated drug target. Reported HIV RNase H inhibitors generally lack significant antiviral activity. We report herein the design, synthesis, biochemical and antiviral evaluations of a new 6-biphenylmethyl

Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H.

Jayakanth Kankanala et al.

European journal of medicinal chemistry, 141, 149-161 (2017-10-17)

Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) is the only HIV enzymatic function not targeted by current antiviral drugs. Although various chemotypes have been reported to inhibit HIV RNase H, few have shown significant antiviral

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货号	GTIN
122505-25G	04061832540894
122505-100G	04061838345530