Quality Level
assay
99%
bp
230 °C (lit.)
mp
96-99 °C (lit.)
solubility
DMF: freely soluble, H2O: freely soluble, aliphatic hydrocarbons: slightly soluble, coal tar bases: freely soluble, lower alcohols: freely soluble, petroleum ether: slightly soluble
SMILES string
Cc1ccnc(N)c1
InChI
1S/C6H8N2/c1-5-2-3-8-6(7)4-5/h2-4H,1H3,(H2,7,8)
InChI key
ORLGLBZRQYOWNA-UHFFFAOYSA-N
Gene Information
human ... NOS1(4842), NOS2(4843), NOS3(4846)
rat ... Nos1(24598)
General description
2-氨基-4-甲基吡啶作为配体,形成甲氧基桥联的铜 (II) 配合物 。
Application
2-氨基-4-甲基吡啶用于合成 2-氨基-4-甲基吡啶-2-羟基苯甲酸盐 。
Biochem/physiol Actions
2-氨基-4-甲基吡啶抑制体外 小鼠 RAW 264.7 细胞分离的诱导型 NO 合成酶的活性 。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 2
flash_point_f
244.4 °F - closed cup
flash_point_c
118 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
W S Faraci et al.
British journal of pharmacology, 119(6), 1101-1108 (1996-11-01)
1. The ability of 2-amino-4-methylpyridine to inhibit the catalytic activity of the inducible NO synthase (NOS II) enzyme was characterized in vitro and in vivo. 2. In vitro, 2-amino-4-methylpyridine inhibited NOS II activity derived from mouse RAW 264.7 cells with
Sherif Y Saad et al.
Chemotherapy, 48(6), 309-315 (2003-04-04)
Nitric oxide (NO) has been shown to play a role in maintaining normal renal function. However, the role of NO in cisplatin (CDDP)-induced nephrotoxicity is still unclear. The aim of the present work was to examine the effect of the
R Boer et al.
Molecular pharmacology, 58(5), 1026-1034 (2000-10-20)
We have investigated various nitric oxide (NO) synthase inhibitors for their affinity and selectivity toward the three human isoenzymes in radioligand binding experiments. Therefore, we developed the new radioligand [(3)H]2-amino-4-picoline to measure binding of these compounds to the three human
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| V900592-500G | 04061831837469 |
| W398403-10KG-K | 04061834398134 |
| W398403-1KG-K | 04061835567485 |
| W398403-5KG-K | 04061834398141 |
| 8045360100 | 04022536385389 |
| 54590-50G-F | 04061832568416 |
| W398403-SAMPLE-K | 04061837537844 |
| V900592-100G | 04061831827866 |
| 8045360250 | 04022536385396 |
| 8045365000 | 04022536889689 |
| 54590-1KG-F | 04061825591803 |
| 54590-250G-F | 04061832568386 |
| 91554-250MG | 04061833263402 |
| 144088-250G | 04061835052219 |
| 144088-50G | 04061835048403 |
| 123080-100G | 04061838722034 |

