Quality Level
assay
98%
bp
251 °C (lit.)
mp
63-65 °C (lit.)
SMILES string
Cc1cc2ccccc2cn1
InChI
1S/C10H9N/c1-8-6-9-4-2-3-5-10(9)7-11-8/h2-7H,1H3
InChI key
FVVXWRGARUACNW-UHFFFAOYSA-N
Gene Information
human ... CYP1A2(1544)
General description
The metabolites of 3-methylisoquinoline were separated by adsorption and reversed-phase high-performance liquid chromatography (HPLC).
Application
3-Methylisoquinoline was used to prepare 3-aminoisoquinoline.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
危险化学品
此项目有
The Preparation of 3-Aminoisoquinoline and Related Compounds1.
Journal of the American Chemical Society, 73(2), 688-689 (1951)
C Stubley et al.
Journal of chromatography, 177(2), 313-322 (1979-09-21)
Adsorption and reversed-phase high-performance liquid chromatography (HPLC) have been successfully used to separate metabolites from the parent heterocycles (isoquinoline, 3-methylisoquinoline, phthalazine, quinazoline, quinoxaline and cinnoline). Retention data are reported. The metabolites, hydroxyazanaphthalenes, which arise as a result of aldehyde oxidase
Markus Brinkmann et al.
Chemical research in toxicology, 32(4), 698-707 (2019-03-22)
Hydroxylation of polyaromatic compounds through cytochromes P450 (CYPs) is known to result in potentially estrogenic transformation products. Recently, there has been an increasing awareness of the importance of alternative pathways such as aldehyde oxidases (AOX) or N-methyltransferases (NMT) in bioactivation
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 129895-1G | 04061826704929 |