主要文件

查看所有文档

142360

4-苄基哌啶

Name: 4-苄基哌啶
Brand: ALDRICH

99%

别名:

苯基(4-哌啶基)甲烷

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₁₂H₁₇N

化学文摘社编号:

31252-42-3

分子量:

175.27

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24848521

EC Number:

250-535-0

Beilstein/REAXYS Number:

132339

MDL number:

MFCD00006006

Assay:

99%

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

description

Drug Control: Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

Quality Level

100

assay

99%

drug control

Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

refractive index

n20/D 1.537 (lit.)

bp

279 °C (lit.)

mp

6-7 °C (lit.)

density

0.997 g/mL at 25 °C (lit.)

functional group

phenyl

SMILES string

C1CC(CCN1)Cc2ccccc2

InChI

1S/C12H17N/c1-2-4-11(5-3-1)10-12-6-8-13-9-7-12/h1-5,12-13H,6-10H2

InChI key

ABGXADJDTPFFSZ-UHFFFAOYSA-N

Gene Information

rat ... Htr2a(29595), Htr2c(25187)

说明

General description

4-苄基哌啶是多巴胺选择性释放剂。它是治疗可卡因成瘾的潜在候选药物。

Application

4-苄基哌啶被用于研究雄性B6C3F1小鼠和Sprague-Dawley大鼠的灌注肝脏中1,3-丁二烯及其氧化代谢产物的代谢。

用于合成以下物质的反应物：

抗增殖剂
GABA吸收抑制剂
吡啶类
组胺 H3 拮抗剂
具有胆碱能和神经保护作用的多功能药物，可用于治疗阿尔茨海默氏症和神经血管疾病
通过亲核取代，发挥抗血清素、抗血小板、血液流变学、抗心律失常和抗氧化作用

Biochem/physiol Actions

4-苄基哌啶能够抑制大鼠脑单胺氧化酶-A和-B的活性。

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

233.6 °F - closed cup

flash_point_c

112 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Quantitative investigation on the metabolism of 1,3-butadiene and of its oxidized metabolites in once-through perfused livers of mice and rats.

Johannes G Filser et al.

Toxicological sciences : an official journal of the Society of Toxicology, 114(1), 25-37 (2009-12-17)

The industrial chemical 1,3-butadiene (BD) is a potent carcinogen in mice and a weak one in rats. This difference is generally related to species-specific burdens by the metabolites 1,2-epoxy-3-butene (EB), 1,2:3,4-diepoxybutane (DEB), and 3,4-epoxy-1,2-butanediol (EBD), which are all formed in

Time-dependent inhibition of rat brain monoamine oxidase by an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine.

Y Arai et al.

Neuroscience letters, 70(2), 255-260 (1986-10-08)

Inhibitory effects of some MPTP and MPP+ analogues on rat brain MAO activity were studied to further clarify the structure-activity relationships of MPTP neurotoxicity. Of the analogues tested, 4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine (CPTP), 4-(4-chlorobenzyl)-pyridine (CBP), 4-benzylpyridine (BPY) and 4-benzylpiperidine (BPIP) dose-dependently inhibited both

Formulation and evaluation of 4-benzylpiperidine drug-in-adhesive matrix type transdermal patch.

Sindhu S Ganti et al.

International journal of pharmaceutics, 550(1-2), 71-78 (2018-08-21)

The objective of our study was to develop a transdermal patch of 4-benzylpiperidine and to evaluate its in vitro transdermal permeation profile. Appropriate pressure sensitive adhesives and additives were selected based on solubility and slide crystallization studies. Release liners and

查看所有相关文献

全球贸易项目编号

货号	GTIN
142360-25G	04061837775369