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145505

α-氰基-4-羟基肉桂酸

97%

别名:

α-CCA, α-CHCA, α-氰基, 4-HCCA, ACCA

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关于此项目

线性分子式:
HOC6H4CH=C(CN)CO2H
化学文摘社编号:
28166-41-8
分子量:
189.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24848731
EC Number:
248-879-1
Beilstein/REAXYS Number:
3271427
MDL number:
MFCD00004204
Assay:
97%
Form:
powder
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Quality Level

100

assay

97%

form

powder

mp

245-250 °C (lit.)

solubility

methanol: soluble 50 mg/mL, clear to slightly hazy, light yellow to yellow

functional group

carboxylic acid, nitrile

storage temp.

2-8°C

SMILES string

OC(=O)\C(=C\c1ccc(O)cc1)C#N

InChI

1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+

InChI key

AFVLVVWMAFSXCK-VMPITWQZSA-N

General description

α-氰基-4-羟基肉桂酸是常用的基质辅助激光解吸电离质谱分析多肽的基质 。抑制蘑菇酪氨酸酶的单酚酶活性和双酚酶活性 。

Application

α-在质谱分析中，使用氰基-4-羟基肉桂酸 (CHC) 作为肽 和核苷酸 的基质。将其用于 NaY 分子筛 对 CHC 的包封。它被用作基质来研究紫杉醇衍生物的活性，使用了几个成熟的 体外 血管生成试验 。

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1B

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCP1551
MKCJ1026
MKCD5516
SHBJ0165
MKCC5911

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Inhibitory effects of α-cyano-4-hydroxycinnamic acid on the activity of mushroom tyrosinase.
Qiu L, et al.
Food Chemistry, 112(3), 609-613 (2009)
G M Hathaway
BioTechniques, 17(1), 150-155 (1994-07-01)
A commercially available, matrix-assisted, laser desorption/ionization (MALDI), time-of-flight mass spectrometer has been used for the successful characterization of picomole quantities of modified deoxyoligonucleotides. The procedure was found to be applicable to the analysis of a variety of modified synthetic structures
S D Patterson et al.
Analytical chemistry, 66(21), 3727-3732 (1994-11-01)
During the analysis of an Asp-N digest of a recombinant hematopoietic growth factor by matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS), we observed pseudomolecular ions corresponding to reduced forms of peptides known to be present only in single disulfide linkages.
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全球贸易项目编号

货号GTIN
145505-5G04061831818666
145505-25G04061838736277