146064
β-丙氨酸
99%, suitable for ligand binding assays
别名:
β-Ala, 3-氨基丙酸
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关于此项目
线性分子式:
NH2CH2CH2COOH
化学文摘社编号:
分子量:
89.09
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
39030936
UNSPSC Code:
12352209
EC Number:
203-536-5
MDL number:
Beilstein/REAXYS Number:
906793
产品名称
β-丙氨酸, 99%
Quality Level
assay
99%
form
powder, crystals or granules
technique(s)
ligand binding assay: suitable
color
white
mp
202 °C (dec.) (lit.)
application(s)
peptide synthesis
SMILES string
NCCC(O)=O
InChI
1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)
InChI key
UCMIRNVEIXFBKS-UHFFFAOYSA-N
Application
β-丙氨酸被用作MAS孤儿相关受体的配体。它还用于某些酵母菌株的培养基中以检测β-丙氨酸营养缺陷体。
Biochem/physiol Actions
内源性 β-氨基酸，是甘氨酸受体的非选择性激动剂和G蛋白偶联孤儿受体TGR7（MrgD）的配体。 β丙氨酸是泛酸的组分。
β丙氨酸是一种 β− 氨基酸，是泛酸的组分，是组氨酰基抗氧化剂二肽肌肽和鹅肌肽生物合成中的限速氨基酸。内源性 β-氨基酸，是甘氨酸受体的非选择性激动剂和G蛋白偶联孤儿受体TGR7（MrgD）的配体。 β-丙氨酸通量通过维持海洋生物、植入前小鼠胚胎和暴露于缺氧应激的哺乳动物细胞的渗透稳定性而发挥细胞保护作用。
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存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Saccharomyces cerevisiae is capable of de Novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine.
White WH
The Journal of Biological Chemistry, 276(14), 10794-10800 (2001)
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), a-, and ?-melanocyte stimulating hormone (a-MSH, and ?-MSH), and the conserved core motif HFRW.
N?hr AC, et al.
Neurochemistry International, 102, 105-113 (2017)
Ammar Majeed et al.
Circulation, 128(21), 2325-2332 (2013-10-02)
The aim of this study was to compare the management and prognosis of major bleeding in patients treated with dabigatran or warfarin. Two independent investigators reviewed bleeding reports from 1034 individuals with 1121 major bleeds enrolled in 5 phase III
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 146064-25G | 04061835365388 |
| 146064-2KG | 04061832718767 |
| 146064-500G | 04061835365395 |