15404
N-Boc-1,4-丁二胺
≥97.0% (GC/NT)
别名:
N-(4-氨丁基)氨基甲酸叔丁酯, N-Boc-1,4-二氨基丁烷
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关于此项目
线性分子式:
(CH3)3COCONH(CH2)4NH2
化学文摘社编号:
分子量:
188.27
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1937878
Assay:
≥97.0% (GC/NT)
Quality Level
assay
≥97.0% (GC/NT)
reaction suitability
reagent type: cross-linking reagent
refractive index
n20/D 1.460
density
0.984 g/mL at 20 °C (lit.)
functional group
Boc, amine
SMILES string
NCCCCNC(OC(C)(C)C)=O
InChI
1S/C9H20N2O2/c1-9(2,3)13-8(12)11-7-5-4-6-10/h4-7,10H2,1-3H3,(H,11,12)
InChI key
ZFQWJXFJJZUVPI-UHFFFAOYSA-N
Application
- 羧基-硅烷涂覆氧化铁纳米颗粒：详述采用N-Boc-1,4-丁二胺修饰氧化铁纳米颗粒用于成像和药物递送(D Stanicki, S Boutry, S Laurent, et al., 2014)。访问文章。
Other Notes
药理活性化合物的制备。亚精胺类似物的制备。C4-间隔基的引入。
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
228.2 °F - closed cup
flash_point_c
109.0 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
商品
Mono-Boc-protected diamines are versatile building blocks for chemical synthesis. Their production is a lot more challenging than the simple reaction scheme might imply, because the Boc-anhydride reagent cannot differentiate between the two identical amino moieties in the substrate.
Y Shai et al.
Biochemistry, 28(11), 4801-4806 (1989-05-30)
In the present study we synthesize 18F-labeled insulin of high specific radioactivity. A new prosthetic group methodology, in which [18F]fluoride displaces a bromide group of 4-(bromomethyl)-benzoylamine intermediates, was used. The 4-(fluoromethyl)benzoyl product was chemically stable. 18F-Labeled insulin retains the essential
L I Kruse et al.
Journal of medicinal chemistry, 32(2), 409-417 (1989-02-01)
In an attempt to identify a soluble oncodazole analogue that could be easily formulated, a series of substituted oncodazoles was synthesized and evaluated for tubulin binding affinity, in vitro cytotoxicity against cultured mouse B-16 cells, and ability to prolong lifespan
Hongyan Guo et al.
Journal of medicinal chemistry, 45(10), 2056-2063 (2002-05-03)
Several iron chelators containing alpha,beta-unsaturated hydroxamic acid motifs appended to a citric acid platform were synthesized. Mycobacterium paratuberculosis was then challenged to grow in the presence of a panel of siderophores (mycobactin J, deferrioxamine B, acinetoferrin, and nannochelin A) and
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 15404-1ML | 04061838118066 |
| 15404-5ML | 04061838118073 |