159220
焦碳酸二乙酯
96% (NT)
别名:
DEP, DEPC, 氧二甲酸二乙酯, 焦炭酸二乙酯, 重碳酸二乙酯
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关于此项目
线性分子式:
O(COOC2H5)2
化学文摘社编号:
分子量:
162.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
216-542-8
Beilstein/REAXYS Number:
637031
MDL number:
Assay:
96% (NT)
Form:
liquid
Quality Level
assay
96% (NT)
form
liquid
refractive index
n20/D 1.398 (lit.)
bp
93-94 °C/18 mmHg (lit.)
density
1.101 g/mL at 25 °C (lit.)
functional group
carbonate
shipped in
wet ice
storage temp.
2-8°C
SMILES string
CCOC(=O)OC(=O)OCC
InChI
1S/C6H10O5/c1-3-9-5(7)11-6(8)10-4-2/h3-4H2,1-2H3
InChI key
FFYPMLJYZAEMQB-UHFFFAOYSA-N
General description
焦碳酸二乙酯选择性地与十字形结构的单链环反应。已有研究表明焦碳酸二乙酯可使核糖核酸酶发生不可逆失活。
Application
焦碳酸二乙酯被用作：
- 核酸酶抑制剂，用于从黄化和绿色植物组织中提取未降解的核酸
- 抗微生物添加剂
- 核糖核酸酶抑制剂
- 组氨酸残基修饰剂
- 将亚胺转化为氨基甲酸酯的试剂
蛋白中His及Tyr残基的修饰试剂。用于dsDNA结构破坏的稳健探针，可与完全或部分未堆叠的碱基发生反应。
Biochem/physiol Actions
在溶液中浓度约为 0.1% (v/v) 时可使 RNase 失活，从而防止 RNA 被降解。
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
156.2 °F - closed cup
flash_point_c
69 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
商品
Solid-state lithium fast-ion conductors are crucial for safer, high-energy-density all-solid-state batteries, addressing conventional battery limitations.
Tetrahedron, 48, 3445-3445 (1992)
P D Pelton et al.
The Journal of biological chemistry, 267(9), 5916-5920 (1992-03-25)
The pH dependence of myo-inositol monophosphatase may indicate a role for histidine residues in the catalytic mechanism (Ganzhorn, A. J., and Chanal, M.-C. (1990) Biochemistry 29, 6065-6071). This possibility was investigated by chemical modification. At pH 6.0 and 25 degrees
Food Sci. Technol., 57, 343-343 (1993)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 159220-25G | 04061838744425 |
| 159220-5G | 04061838744432 |
| 159220-100G | 04061838744418 |